Results 161 to 170 of about 241,090 (306)

Therapeutic potential of hydroxybenzoic acid and lentinan in mitigating glucocorticoid-induced osteoporosis: an experimental study [PDF]

Büşra Söyler, Tuğba Melike Parlak, İbrahim BÜYÜKTAŞKAPULU, Muhammed Demircioğlu, Muhammet Bahaeddi̇n Dörtbudak, Ali Koçyiğit, İsmail Demircioğlu, Annalisa Chiavaroli, Burak Dik   +8 more
openalex   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Glucocorticoids augment survival and proliferation of tumor cells.

, 2012
BACKGROUND: Glucocorticoids are widely used for cancer patients, although they can reduce the efficacy of anticancer treatment. MATERIALS AND METHODS: We characterized non-apoptotic actions of glucocorticoids on tumor cell lines, primary tumor cells and ...
Jeremias, I., Amtmann, E., Boeckeler, E., Behrends, U., Ehrhardt, H., Gündisch, S.   +5 more
core  

Sarcopenia and Sarcopenic Obesity in Postmenopausal Women: Limitations of BMI as a Predictor of Sarcopenic Obesity

AGING MEDICINE, EarlyView.
The prevalence of sarcopenia and sarcopenic obesity is large among community‐dwelling postmenopausal women, and lower body mass index is a significant predictor of both. The finding that low body mass index predicts both sarcopenia and sarcopenic obesity, highlights the limitation of body mass index as a measure of adiposity in the assessment of ...
Remya Rajan, Kripa Cherian, Thomas Paul, Hesarghatta Shyamasunder Asha, Arun Jose, Grace Rebekah, Nihal Thomas, Nitin Kapoor   +7 more
wiley   +1 more source

Optical Control of the Glucocorticoid Receptor Activity With a Photoswitchable Agonist

Angewandte Chemie, EarlyView.
A photoswitchable glucocorticoid receptor agonist enables optical control of receptor activity, achieving picomolar potency and partial agonism that preferentially maintains anti‐inflammatory signaling over canonical transcriptional activation. ABSTRACT Glucocorticoids (GCs) are widely prescribed anti‐inflammatory agents whose clinical utility is ...
Zoe Sessions, Chloé Van Leene, Dorien Clarisse, George Keen, Agnė Šveistytė, Dinahlee Saturnino Guarino, Robert H. Mach, Karolien De Bosscher, Dirk Trauner   +8 more
wiley   +2 more sources

Corticosteroids, serum proteins, and the next phase of precision medicine in IgA nephropathy. [PDF]

Clin Kidney J
Zoccali C, Floege J.
europepmc   +1 more source

早期经验、表观遗传甲基化与跨代行为先验的传递边界:从糖皮质激素受体编程、双生子方差分解到社会学习信道与儒家家风熏习观考辨 | Early Experience, Epigenetic Methylation and the Limits of Intergenerational Transmission: From Glucocorticoid-Receptor Programming and Twin Variance Decomposition to Social-Learning Channels, Read Beside Classical Chinese Family Instruction

Yafu Fan
openalex   +1 more source

Probiotic Extracellular Vesicles Enable Oral Alendronate Therapy for Glucocorticoid‐Induced Osteoporosis [PDF]

Jing Ruan, Yilei Ma, Ke Zhang, Baoting Wu, Ting Xu, Xinlu Wang, Zhipeng Li, Shiyu Xu, Jiali Xu, Xianmei Yu, Hanbing Wang, Rongbing Chen, Yijing Cheng, Zhigang Zheng, Dongjuan He, Da Sun, Cheng Luo   +16 more
openalex   +1 more source

Chromosomal Abnormalities, Drug Sensitivity and Resistance in Hematological Malignancies: A Comprehensive Overview by the Francophone Group of Hematological Cytogenetics (GFCH)

American Journal of Hematology, EarlyView.
ABSTRACT Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...
Florence Nguyen‐Khac, Audrey Bidet, Elise Chapiro, Nathalie Douet‐Guilbert, Jean‐Baptiste Gaillard, Nada Assaf, Nathalie Auger, Hend Chaker, Jasmine Chauzeix, Inge Govaerts, Hippolyte Guérineau, Christine Lefebvre, Pauline Roynard, Hélène Guermouche, Lucienne Michaux, Marie‐Bérengère Troadec, Lauren Véronèse   +16 more
wiley   +1 more source

WNT5A-Associated Osteogenic Enhancement Contributes to the Protective Effects of OPG-Fc in Glucocorticoid-Associated Femoral Head Osteonecrosis

Wei Shi, Zeyu Dai, Chaobo Li, Yongqing Xu   +3 more
openalex   +1 more source