Results 151 to 160 of about 241,090 (306)

Glucocorticoids in the Management of Bronchial Asthma: From Pathophysiology to Precision Medicine. [PDF]

open access: yesBiomedicines
Stâncoi AA   +6 more
europepmc   +1 more source

Intraoperative glucocorticoids confound surgical biopsy transcriptomics [PDF]

open access: gold
Frederik T. Larsen   +12 more
openalex   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng   +4 more
wiley   +1 more source

Amcinonide Exhibits Antitumor Effects in Radioresistant Colorectal Cancer Through the circRNF10/miR‐296‐5p/Snail Axis

open access: yesAdvanced Science, EarlyView.
Amcinonide (AMC), the FDA‐approved corticosteroid, was identified as a repurposed agent for radiation‐resistant colorectal cancer. AMC suppresses radiation‐induced epithelial–mesenchymal transition, migration, and invasion via the circRNF10/miR‐296‐5p/Snail axis.
Hyun Jeong Seok   +4 more
wiley   +1 more source

Salivary Citrate Deficiency Defines an Endogenous Dentin Remineralization Failure State Through Glandular MT1/2‐Zn2+‐ACO2 Dysregulation

open access: yesAdvanced Science, EarlyView.
Salivary citrate deficiency in early‐stage Sjögren's syndrome accompanies impaired dentin remineralization despite preserved salivary flow and mineral availability. Matched‐ion experiments reveal disrupted mineral organization and reduced dentin recovery at disease‐associated citrate levels.
Ran You   +8 more
wiley   +1 more source

Role of the ACTH-SF1/NR5A1-NRF2 axis in glucocorticoid-induced adrenocortical cell death through mitochondrial ROS accumulation

open access: gold
Naohiro Uchida   +14 more
openalex   +1 more source

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