Results 171 to 180 of about 288,891 (362)

Innate Lymphoid Cell Phenotypic and Functional Alterations in Patients With Systemic Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood disease classically attributed to innate immune cell dysregulation. This study aimed to elucidate the role of innate lymphoid cells (ILCs), including natural killer (NK) cells and helper‐ILCs (hILCs), in sJIA during clinically inactive disease (CID) through phenotypic and ...
Linda Quatrini   +19 more
wiley   +1 more source

Mode of Action of Glucocorticoids

open access: hybrid, 1964
Paul D. Ray   +2 more
openalex   +1 more source

Maintenance of remission after tocilizumab withdrawal in patients with glucocorticoid‐dependent polymyalgia rheumatica

open access: yesArthritis &Rheumatology, Accepted Article.
Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) in glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC use and disease activity at 24 weeks. This study aimed to assess relapse rates after stopping TCZ in patients achieving remission at week 24.
Baptiste Chevet   +24 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Partial purification of a glucocorticoid receptor. [PDF]

open access: bronze, 1975
Douglas Failla   +2 more
openalex   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens   +14 more
wiley   +1 more source

Effect of glucocorticoids on the oxidative desaturation of fatty acids by rat liver microsomes.

open access: yesJournal of Lipid Research, 1979
The effect of glucocorticoids on the oxidative desaturation of fatty acids by liver microsomal preparations of rats has been studied. Hydrocortisone produced a significant decrease in the conversion of [1-14C]linoleic acid to gamma-linolenic acid and [1 ...
I N de Gómez Dumm   +2 more
doaj  

Skeletal muscle metabolism in hypokinetic rats [PDF]

open access: yes
Muscle growth, protein metabolism, and amino acid metabolism were studied in various groups of rats. Certain groups were adrenaliectomized; some rats were suspended while others (the controls) were weight bearing. Results show that: (1) metabolic changes
Tischler, M. E.
core   +1 more source

Changes in Pain Sensitization after DMARD therapy are Associated with Changes in Disease Activity in Established Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Abnormalities in pain regulatory mechanisms are common in patients with rheumatoid arthritis (RA). We investigated whether pain sensitization changes after treatment with a disease modifying anti‐rheumatic drug (DMARD) and explored associations between changes in pain sensitization and disease activity.
Burcu Aydemir   +10 more
wiley   +1 more source

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