Results 41 to 50 of about 288,891 (362)
Consequences of the Lack of IL-10 in Different Endotoxin Effects and its Relationship With Glucocorticoids [PDF]
, 2019 Sepsis constitutes one of the major causes of death in ICUs. In sepsis induced by gram-negative, although lipopolysaccharide (LPS) initially induces an exacerbated secretion of proinflammatory cytokines leading to endotoxic shock and death resembling a ...
Barrientos, Gabriela Laura +10 more
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Fibrotic pathways and fibroblast-like synoviocyte phenotypes in osteoarthritis
Frontiers in ImmunologyOsteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte formation, cartilage degradation, and structural and cellular alterations of the synovial membrane.
Alexandra Damerau +7 more
doaj +1 more source
Risk Management and Healthcare Policy, 2023 Xiaoyi Li,1,* Zhen Zeng,2,* Xingying Fan,1,3 Wenju Wang,4 Xiaobo Luo,4 Junli Yang,1 Yue Chang1,3,* 1School of Medicine and Health Management, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 2Second ...
Li X +6 more
doaj
Regulation of triglyceride metabolism by glucocorticoid receptor
Cell & Bioscience, 2012 Glucocorticoids are steroid hormones that play critical and complex roles in the regulation of triglyceride (TG) homeostasis. Depending on physiological states, glucocorticoids can modulate both TG synthesis and hydrolysis.
Wang Jen-Chywan +3 more
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A general introduction to glucocorticoid biology [PDF]
, 2019 Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their broad physiological and therapeutic effects, GCs bind to the GC receptor (GR) which belongs to the nuclear receptor ...
Libert, Claude +2 more
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Scientific Reports, 2017 Chronic administration of glucocorticoids has been shown to render individuals highly susceptible to mycobacterial infection and lead to reactivation of latent bacilli.
Jinli Wang +7 more
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Life Course Impact of Glucocorticoids During Pregnancy on Muscle Development and Function
Frontiers in Animal Science, 2021 Maternal stress, such as maternal obesity, can induce severe gestational disease and hormonal disorder which may disrupt fetal organ maturation and further cause endangered early or future health in offspring.
Yang Liu, Qiyue Ding, Wei Guo
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Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]
, 1973 The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L +7 more
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Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword
Cells, 2013 First described for their metabolic and immunosuppressive effects, glucocorticoids are widely prescribed in clinical settings of inflammation. However, glucocorticoids are also potent inducers of apoptosis in many cell types and tissues. This review will
Amanda L. Gruver-Yates +1 more
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Glucocorticoid receptor action in metabolic and neuronal function [version 1; referees: 3 approved] [PDF]
, 2017 Glucocorticoids via the glucocorticoid receptor (GR) have effects on a variety of cell types, eliciting important physiological responses via changes in gene expression and signaling.
Garabedian, Michael J +2 more
core +3 more sources