Results 71 to 80 of about 415,196 (303)

Evaluation of glucocorticoids utilization in central kerala using pharmacy sales overview

Indian Journal of Endocrinology and Metabolism, 2021
Background: Misuse of prescription drugs is a major public health problem in India and developing countries. Emerging evidence indicates that glucocorticoids are a class of drugs that are silently misused. These drugs are inexpensive and easily available
Sara Mathew, Philip Finny, Abel K Samuel Johnson, Mridula Maria, Preethy S Samuel, Lois J Armstrong, Alice David   +6 more
doaj   +1 more source

Postoperative glucocorticoids in patients with acute type A aortic dissection (GLAD): study protocol for a prospective, single-center, randomized controlled trial

BMC Anesthesiology, 2023
Background Patients receiving surgical treatment of acute type A Aortic Dissection (aTAAD) are common to suffer organ dysfunction in the intensive care unit due to overwhelming inflammation.
Yi-zhi Deng, Ming-hao Luo, Jing-chao Luo, Jia-kun Li, Jia-qi Chen, Yi-jie Zhang, Jun-yi Hou, Ying Su, Guo-wei Tu, Zhe Luo   +9 more
doaj   +1 more source

Effects of Glucocorticoids on Postoperative Neurocognitive Disorders in Adult Patients: A Systematic Review and Meta-Analysis

Frontiers in Aging Neuroscience, 2022
BackgroundPostoperative neurocognitive disorders (PNDs) is common among surgical patients, however, the effect of glucocorticoids for preventing PNDs is not clear.
Xiaoyu Xie, Xiaoyu Xie, Rui Gao, Rui Gao, Hai Chen, Hai Chen, Xueying Zhang, Xueying Zhang, Xingwei Cai, Xingwei Cai, Changteng Zhang, Changteng Zhang, Changliang Liu, Changliang Liu, Tao Zhu, Tao Zhu, Chan Chen, Chan Chen   +17 more
doaj   +1 more source

Role of Glucocorticoids and Glucocorticoid Receptors in Glaucoma Pathogenesis

Cells, 2023
The glucocorticoid receptor (GR), including both alternative spliced isoforms (GRα and GRβ), has been implicated in the development of primary open-angle glaucoma (POAG) and iatrogenic glucocorticoid-induced glaucoma (GIG). POAG is the most common form of glaucoma, which is the leading cause of irreversible vision loss and blindness in the world ...
Pinkal D. Patel, Bindu Kodati, Abbot F. Clark   +2 more
openaire   +3 more sources

IL-1α and TNF-α Down-Regulate CRH Receptor-2 mRNA Expression in the Mouse Heart [PDF]

, 2001
Two receptors (CRH receptor type 1 and CRH receptor type 2) have been identified for the stress-induced neuropeptide, CRH and related peptides, urocortin, and urocortin II.
Coste, Sarah C., Heldwein, Kurt A., Stenzel-Poore, Mary P., Stevens, Susan L., Tobar-Dupres, Eric   +4 more
core   +2 more sources

Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy

BMC Cancer, 2008
Background Glucocorticoids are often used in the treatment of nonhematologic malignancy. This review summarizes the clinical evidence of the effect of glucocorticoid therapy on nonhematologic malignancy. Methods A systematic review of clinical studies of
Keith Bruce D
doaj   +1 more source

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding, Eugene Akujuru, Feliciano Protasi, Gabriel Mutungi, Goldberg AL, Lewis Arthurton, Simona Boncompagni, Timothy Pearson, Wing SS   +8 more
core   +1 more source

Impact of glucocorticoid on neurogenesis

Neural Regeneration Research, 2017
Neurogenesis is currently an area of great interest in neuroscience. It is closely linked to brain diseases, including mental disorders and neurodevelopmental disease.
Haruki Odaka, Naoki Adachi, Tadahiro Numakawa   +2 more
doaj   +1 more source

Aerobic Biodegradation of Four Groups of Steroid Hormones in Activated Sludge

Journal of Chemistry, 2020
Steroid hormones in the environment have obtained considerable attention, as they can be harmful to aquatic organisms at very low concentrations. An analytical method was developed for simultaneously monitoring four estrogens, seven androgens, seven ...
Jiaxin Zhang, Jun Luo, Hong Chang
doaj   +1 more source

Glucocorticoids for treating paediatric pulmonary hypertension: A novel use for a common medication [PDF]

, 2017
Laboratory investigations have shown the role of inflammation in the pathogenesis of pulmonary hypertension and improvement after anti-inflammatory drugs.
Aggarwal, Manish, Grady, Ronald M
core   +2 more sources