Results 121 to 130 of about 21,204 (221)

Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant. [PDF]

Mol Metab
Santoleri D, Traynor S, Calhoun RP, Gavin MJ, Merrick D, Seale P, Titchenell PM.   +6 more
europepmc   +1 more source

Targeting the Glucokinase-Glucokinase Regulatory Protein Axis: Pharmacophore-Based Identification of Novel Antidiabetic Small Molecules. [PDF]

ACS Med Chem Lett
Paliwal A, Paliwal S, Sharma S, Mishra AK, Jain S.   +4 more
europepmc   +1 more source

Clinical and pathomorphological characterisation of two diabetic mouse models derived from the Munich ENU mouse mutagenesis project [PDF]

, 2010
Bürck, Lelia van
core   +1 more source

Recent advances in pancreatic β-cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation. [PDF]

J Diabetes Investig
Kido N, Asahara SI.
europepmc   +1 more source

Personalized management of glucokinase-related monogenic diabetes (GCK-MODY) during pregnancy: a case report. [PDF]

Front Endocrinol (Lausanne)
Bolas AF, Torres JO, Bogalho P, Silva-Nunes J.   +3 more
europepmc   +1 more source

The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte

Glucokinase has a very high flux control coefficient (greater than unity) on glycogen synthesis from glucose in hepatocytes (Agius et al., J. Biol. Chem. 271, 30479-30486, 1996). Hepatic glucokinase is inhibited by a 68-kDa glucokinase regulatory protein
Agius L; Mukhtar M; De La Iglesia N; Seoane J; Guinovart JJ
core   +2 more sources

Crystal structures of Escherichia coli glucokinase acetylation-mimicking variants and insights into the impact of acetylation. [PDF]

Acta Crystallogr F Struct Biol Commun
Andrews J, Sakon J, Fan C.
europepmc   +1 more source

Alcohol Exposure Alters the Ghrelin System: In Vitro Mechanistic Insights Into Impaired Glucose Sensing and Enhanced Ghrelin Secretion. [PDF]

Alcohol Clin Exp Res (Hoboken)
Mahalingam S, Bellamkonda R, Kharbanda KK, Ethiraj O, Casey CA, Rasineni K.   +5 more
europepmc   +1 more source

Characterisation of a cold-adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS-131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation. [PDF]

FEBS J
Yato A, Kato Y, Hayashi F, Asaka R, Ogawa A, Oda T, Tsuji S, Unno M, Soh N, Watanabe K, Horitani M.   +10 more
europepmc   +1 more source

Elucidating the proteomic pathways linking childhood body mass index with type 2 diabetes: a Mendelian randomization and recall-by-genotype study. [PDF]

Int J Epidemiol
Chen S, Liang Y, Luo S, Zheng J, Yoshiji S, Power GM, Xu Z, Burgess S, Cowling BJ, Lam HS, Li AM, Leung GM, Schooling CM, Au Yeung SL.   +13 more
europepmc   +1 more source