Hepatic Gluconeogenesis and the Antidepressant Effects of Exercise: A Narrative Review [PDF]
MetabolitesBackground: Research indicates that hepatic gluconeogenesis mediates metabolic coupling between the liver and muscles via the Cori cycle and participates in liver–brain axis communication through its metabolic products and regulatory networks, thereby ...
Hongyu Gong +8 more
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Regulation and clinical manifestations of gluconeogenesis dysfunction [PDF]
NPJ Metab Health DisThe liver is the principal organ responsible for maintaining systemic glucose homeostasis through the integrated regulation of gluconeogenesis, glycogenolysis, glycogenesis, and glycolysis.
Natalia Bobok
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Carbohydrate and lipid metabolism in insulin resistant states and the development of in vivo magnetic resonance spectroscopic techniques for the analysis of gluconeogenesis and glycogen synthesis [PDF]
, 1995 PhDThis thesis will provide new information on carbohydrate and lipid metabolic control in various related physiological states both in vitro and in vivo in the rat model.
Changani, K.K., Changani, Kishore Kumar
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Regulation of gluconeogenesis in type 2 diabetes mellitus: An investigation of the role of corticosteroids? [PDF]
, 2012 PhDType 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormones and metabolites. Over expression of key gluconeogenic enzymes, such as PEPCK, cause features of T2DM including obesity and insulin resistance ...
Nayuni, Nanda Kishore Babu
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Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice
Cells, 2022 Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isoforms,
Marilina Florio +11 more
doaj +1 more source
Differential Metabolism of Glycerol Based on Oral versus Intravenous Administration in Humans
Metabolites, 2022 Glycerol can be metabolized to glucose via gluconeogenesis or lactate via glycolysis. It is unknown if glycerol is metabolized similarly in the portal and systemic circulations in humans.
Ankit Shah +2 more
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Cells, 2023 Nanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs ...
Sílvia Soares +7 more
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Gluconeogenesis and Ammonia Production in the Isolated Perfused Rat Kidney : The Effect of Starvation, Acidosis and Diabetic Ketosis [PDF]
, 1984 1984-03Isolated rat kidneys were perfused with a cell-free perfusate, and their creatinine clearance was found to be 106 μl/min./g wet weight. Gluconeogenesis from pyruvate, lactate, fructose, α-oxoglutarate, oxaloacetate, glutamate and glutamine as the ...
SANO, TAKAHISA +6 more
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Optimized 3D Culture of Hepatic Cells for Liver Organoid Metabolic Assays
Cells, 2021 The liver is among the principal organs for glucose homeostasis and metabolism. Studies of liver metabolism are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions.
Christian Moya Gamboa +5 more
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The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes [PDF]
Animal Bioscience, 2023 Objective Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects ...
Rui Pang +7 more
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