Future directions for the management of pain in osteoarthritis. [PDF]
, 2014 Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T +23 more
core +1 more source
Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
Mass Spectrometry Reviews, EarlyView.ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source
RePol: A high-throughput screen for optimizing membrane protein solubilization and purification using polymers. [PDF]
Protein SciAbstract Extraction and purification of membrane proteins has for a long time represented a significant challenge. Polymer‐based extraction methods, like those using styrene maleic acid co‐polymers have provided a fertile approach to generate samples that include the local lipid environment surrounding the protein.
Evans A +7 more
europepmc +2 more sources
The binding of glycosaminoglycans to peptides : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1994 The overall aim this study was to examine the possibility of using immobilised polypeptide chains to fractionate/separate Glycosaminoglycans (GAG's) from mixtures. Initially individual samples of three GAG classes (chondroitin sulphate, dermatan sulphate
Taylor, Grant John
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Small, EarlyView.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Glucosamine Enhances TRAIL-Induced Apoptosis in the Prostate Cancer Cell Line DU145
Medicines, 2019 Background: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells in cancer patients. However, patients often develop TRAIL resistance; thus, agents that can sensitize cells to TRAIL therapy would be ...
Chao Sun +3 more
doaj +1 more source
Efficacy and safety of prednisolone and chloroquine Add on therapy in osteoarthritis of the knee treated with fixed Dose combination of Glucosamine and chondroitin sulfate [PDF]
Background & ObjectiveOsteoarthritis is the most common type of joint disorder and also the main reason to consult Rheumatologists. Furthermore, a high level of weakness especially among elderly is due to OA.
بهلولی, شهاب +2 more
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A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses [PDF]
, 1993 The primary structure of the peptidoglycan and the teichoic acids of two coryneform isolates from the surface flora of French cooked cheeses, CNRZ 925 and CNRZ 926, have been determined.
Accolas, Jean-Pierre +3 more
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Fusion of secretory vesicles isolated from rat liver [PDF]
, 1978 Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam +75 more
core +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Primary metabolites in root exudates are essential for plant nutrition and rhizosphere microbiome function, potentially responding sensitively to climate warming. However, the effects of long‐term soil warming on exudate metabolites in forests remain unclear.
Xiaofei Liu +6 more
wiley +1 more source