Results 141 to 150 of about 139,522 (368)

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

open access: yesIbrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka   +5 more
wiley   +1 more source

Glucosamine protects against neuronal but not vascular damage in experimental diabetic retinopathy

open access: yesMolecular Metabolism, 2021
Objective: Glucosamine, an intermetabolite of the hexosamine biosynthesis pathway (HBP), is a widely used nutritional supplement in osteoarthritis patients, a subset of whom also suffer from diabetes. HBP is activated in diabetic retinopathy (DR).
Rachana Eshwaran   +10 more
doaj  

Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme. [PDF]

open access: yes, 2020
Massively parallel, quantitative measurements of biomolecular activity across sequence space can greatly expand our understanding of RNA sequence-function relationships. We report the development of an RNA-array assay to perform such measurements and its
Andreasson, Johan OL   +3 more
core  

Characterization of Newly Discovered Polyester Polyurethane‐Degrading Methylobacterium aquaticum Strain A1

open access: yesJournal of Basic Microbiology, EarlyView.
ABSTRACT In this study, we present Methylobacterium aquaticum A1, a novel strain capable of degrading polyester polyurethane (PE‐PUR). The attachment of M. aquaticum A1 to PE‐PUR and its degradation capabilities were verified using Scanning Electron Microscopy (SEM) and Fourier‐Transform Infrared Spectroscopy (FT‐IR).
Seong Hyeon Lee   +4 more
wiley   +1 more source

Magnetic Mixed Micelles Composed of a Non-Ionic Surfactant and Nitroxide Radicals Containing a D-Glucosamine Unit: Preparation, Stability, and Biomedical Application

open access: yesPharmaceutics, 2019
Metal-free magnetic mixed micelles (mean diameter: < 20 nm) were prepared by mixing the biocompatible non-ionic surfactant Tween 80 and the non-toxic, hydrophobic pyrrolidine-N-oxyl radicals bearing a D-glucosamine unit in pH 7.4 phosphate-buffered ...
Kota Nagura   +11 more
doaj   +1 more source

Chitosan/Platelet‐Rich Plasma Implants in an Ovine Arthroscopic Model of Meniscus Repair

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Despite the availability of various repair techniques, many meniscal tears remain irreparable. A freeze‐dried chitosan‐based formulation reconstituted in autologous platelet‐rich plasma has shown potential in preclinical studies for enhancing suture‐based meniscus repair.
Margaux Delvaux   +6 more
wiley   +1 more source

In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino   +6 more
wiley   +1 more source

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