Results 171 to 180 of about 139,522 (368)

Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma

open access: yesSmall Science, EarlyView.
Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim   +11 more
wiley   +1 more source

Analysis of the Health and Budgetary Impact of Chondroitin Sulfate Prescription in the Treatment of Knee Osteoarthritis Compared to NSAIDs and COXIBs

open access: yesClinicoEconomics and Outcomes Research, 2020
Carlos Rubio-Terrés,1 Miguel Bernad Pineda,2 Marta Herrero,3 Carlos Nieto,3 Darío Rubio-Rodríguez1 1Health Value, Madrid, Spain; 2Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain; 3Reig Jofre, Barcelona ...
Rubio-Terrés C   +4 more
doaj  

Hyperspectral Raman imaging to understand patterns in dried biofluids in Alzheimer's disease

open access: yesVIEW, EarlyView.
Raman spectroscopy is commonly used to identify biomarkers in biological fluids, often focusing on the outer ring of dried droplets due to molecular accumulation from the coffee ring effect. However, this approach may overlook important spectral information, so hyperspectral Raman mapping is used to analyze the entire droplet and identify optimal ...
Eneko Lopez   +8 more
wiley   +1 more source

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth. [PDF]

open access: yes, 1987
Neuronal responses to extracellular matrix (ECM) constituents are likely to play an important role in nervous system development and regeneration. We have studied the interactions of a neuron-like rat pheochromocytoma cell line, PC12, with ECM protein ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core  

Tree species and soil depth affect microbial necromass contribution to soil organic matter in temperate forest soils, surpassing the impact of microbial and faunal community composition

open access: yesFunctional Ecology, EarlyView.
Abstract Forest management and climate change inevitably lead to shifts in the composition of temperate forest stands from coniferous to deciduous species, potentially affecting the crucial role of forest soil organic carbon (SOC) stocks in mitigating climate change.
Veronika Jílková   +7 more
wiley   +1 more source

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. [PDF]

open access: yes, 2019
Hepcidin is a liver-derived peptide hormone that controls systemic iron homeostasis. Its expression is regulated by the bone morphogenetic protein 6 (BMP6)/SMAD1/5/8 pathway and by the proinflammatory cytokine interleukin 6 (IL6).
Anower-E-Khuda, Ferdous   +8 more
core  

Mangrove restoration enhances blue carbon sequestration and its stability in a subtropical tidal wetland

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Mangrove forests are among the most productive blue carbon (C) ecosystems. While mangrove restoration is recognized for its potential to increase coastal blue C storage, its effects on soil organic C (SOC) stability and sources remain poorly understood.
Xingyun Huang   +14 more
wiley   +1 more source

Effect of Chitosan Degradation Products, Glucosamine and Chitosan Oligosaccharide, on Osteoclastic Differentiation

open access: yesBioTech
Chitosan, a natural cationic polysaccharide derived from crustaceans and shellfish shells, is known for its advantageous biological properties, including biodegradability, biocompatibility, and antibacterial activity. Chitosan and its composite materials
Tomoharu Takeuchi   +2 more
doaj   +1 more source

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