Results 61 to 70 of about 25,891 (219)

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Effect of Glucosamine Sulfate Alone and Combined with Moderate Intensity Exercise on Serum Levels of CS 846 Epitope and Cartilage Oligomeric Matrix Protein in a Rat Model of Osteoarthritis

Medical Laboratory Journal, 2021
Background and objectives: Osteoarthritis is the result of a defect in synovial membrane-covered joint tissues. The purpose of this study was to investigate effects of glucosamine sulfate alone and combined with moderate intensity exercise on serum ...
babak Biniaz, hajar abaszadeh, parvin farzanegi   +2 more
doaj  

On the anticoagulant and antiaggregatory properties of a glucosamine sulfate molecule

Современная ревматология, 2019
Glucosamine is part of the human metabolome required for the biosynthesis of polymer glycosaminoglycans in connective tissue. In addition, the glucosamine molecule itself has anti-inflammatory and regenerative properties.
I. Yu. Torshin, A. M. Lila, O. A. Gromova, A. V. Naumov, A. N. Gromov   +4 more
doaj   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Arterial smooth muscle cell proteoglycans synthesized in the presence of glucosamine demonstrate reduced binding to LDL1

Journal of Lipid Research, 2002
Atherosclerosis is the main cause of morbidity and mortality in diabetes, yet the underlying mechanisms remain unclear. Retention of atherogenic lipoproteins by vascular proteoglycans is thought to play a key role in the development of atherosclerotic ...
Lisa R. Tannock, Peter J. Little, Thomas N. Wight, Alan Chait   +3 more
doaj   +1 more source

Taxogenomic Characterization and Comparative Genomic Analysis of Hermanozyma buritii sp. nov., f.a., a Yeast Species Isolated From Plants and Soil

Yeast, EarlyView.
Isolation of the novel yeast species Hernanozyma buritii sp. nov. from soil and plant in Brazil, followed by phylogenetic characterization and genome analysis, highlighting its relationship with closely related taxa and genomic features associated with mating, pulcherriminic acid biosynthesis, and iron‐dependent pigmentation.
Vitória Petra de O. Barros, Ana Raquel O. Santos, Júlio Ricardo M. Silva, Paula B. Morais, Thiago M. Batista, Daniela L. Souza, Rosangela Santa‐Brígida, Marlúcia B. Martins, Glória R. Franco, Marc‐André Lachance, Carlos A. Rosa, Melissa Fontes Landell   +11 more
wiley   +1 more source

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine

Journal of Pharmaceutical Analysis, 2012
A selective precolumn derivatization liquid chromatography–tandem mass spectrometric (LC–MS/MS) method for the determination of glucosamine in human plasma and urine has been developed and validated.
Min Song, Tai-Jun Hang, Cheng Wang, Lin Yang, Ai-Dong Wen   +4 more
doaj   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Do combined glucosamine sulfate and chondroitin sulfate supplements affect condylar remodelling during functional appliance therapy?

Australasian Orthodontic Journal, 2018
The purpose of this study was to qualitatively and quantitatively analyse the effect of glucosamine sulfate and chondroitin sulfate supplements on condylar remodelling in conjunction with bite-jumping functional appliance therapy in rats.
Barley Gosia, Shen Gang, Almuzian Mohammed, Jones Alan, Oliver Rema, Petocz Peter, Walsh William R., Darendeliler M. Ali   +7 more
doaj   +1 more source