Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.This network meta‐analysis of 4 randomized controlled trials (14,348 adults with type 2 diabetes, with or without established atherosclerotic cardiovascular disease) compared all clinically relevant doses of tirzepatide (1, 5, 10, 15 mg) against dulaglutide (0.75, 1.5, 4.5 mg).
Ahmed W. Hageen +13 more
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Tirzepatide and Weight Management
JK ScienceTirzepatide is a once-weekly dual agonist, that acts on glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors.
Vishal R. Tandon, Annil Mahajan
doaj
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.DPP‐4 Inhibitors associated withheart failure events in patients with type‐2 diabetes. This study found statistically insignificant summary effect for all DPP‐4 inhibitors combined but found asignificant association of saxagliptin with heart failure events (RR = 1.24, 95% CI 1.05–1.47). Results are to be interpreted with caution.
Shishir Nepal, Shiva Prasad Nepal
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Interaction between fatty pancreas disease and genetically predicted glucose-dependent insulinotropic polypeptide on incident type 2 diabetes: evidence from the UK Biobank. [PDF]
Front Endocrinol (Lausanne)Wang X +8 more
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The Evolution of Medications for Obesity Management
JGH Open, Volume 10, Issue 9, September 2026.ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
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Glucose-Dependent Insulinotropic Polypeptide and Glucagon After Weight Loss Induced by Diet or Bariatric Surgery. [PDF]
Obesity (Silver Spring)Finn A +4 more
europepmc +1 more source
The impact of cinnamon on glucose levels and alcohol cravings in early recovery [PDF]
, 2012 Morshead-Metelica, Jeanna
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Metabolic Syndrome: From Mechanisms to Therapeutic Interventions
MedComm, Volume 7, Issue 9, September 2026.A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Florian Kahles +9 more
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Glucose-Dependent Insulinotropic Polypeptide Receptors Are Expressed in the Lateral Septum and Reduce Electrically-Evoked Dopamine Release as well as the Ability of Cocaine to Increase Extracellular Dopamine. [PDF]
ACS Chem NeurosciBuchanan AM +8 more
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