Results 151 to 160 of about 64,864 (253)

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1826-1835, March 2026.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone   +5 more
wiley   +1 more source

Melatonin Is Bound to a Glycolytic Protein Complex via Tdh2p During Fermentation in Saccharomyces cerevisiae

open access: yesJournal of Pineal Research, Volume 78, Issue 2, March 2026.
ABSTRACT Melatonin (MEL) is a multifunctional bioactive compound known for its antioxidant properties and regulatory roles in both animal and microbial systems. Although MEL has been shown to interact with glycolytic enzymes in yeast, the molecular basis and physiological relevance of these interactions remain unclear.
Sandra Martín‐Esteban   +5 more
wiley   +1 more source

Characterisation of Th1/Th2 type, glucose-6-phosphate isomerase reactive T cells in the generation of rheumatoid arthritis [PDF]

open access: bronze, 2006
Yuko Kori   +9 more
openalex   +1 more source

Phytosulfokine signalling blocks mycotoxin toxicity in Arabidopsis and mediates suppression of cell death activated by bacterial microbe‐associated molecular patterns

open access: yesNew Phytologist, Volume 249, Issue 5, Page 2515-2530, March 2026.
Summary Fumonisin B1 (FB1) is a mycotoxin that disrupts ceramide biosynthesis and kills plants. Prior activation with bacterial microbe‐associated molecular patterns (MAMPs), such as components of bacterial flagella, effectively suppresses FB1‐induced cell death.
Ali O. Alqarni   +3 more
wiley   +1 more source

Reassessing Transketolase Assays: Methodological Considerations for Detecting Functional Thiamine Deficiency

open access: yesAnnals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
Transketolase (TKT) activity provides a functional measure of thiamine status by integrating cofactor availability, enzyme abundance, and catalytic capacity. TKT catalyzes thiamine diphosphate (TDP)‐dependent reactions in the nonoxidative pentose‐phosphate pathway and requires magnesium for optimal activity.
Katie A. Edwards
wiley   +1 more source

Engineering Cyanobacteria for High‐Yield Photosynthetic Isoprene Production With Long‐Term Phenotypic Stability

open access: yesPlant Biotechnology Journal, Volume 24, Issue 3, Page 1014-1030, March 2026.
Center: Cyanobacterial isoprene production from CO2 and sunlight. Top: CRISPR‐editing for generation of markerless production strains. Top right: Long‐term production assay for strain stability assessment. Bottom right: Engineering of MEP pathway and surrounding metabolism for bottleneck idenfication. Bottom left: Relief of bottleneck by overproduction
Kim N. Janssen   +6 more
wiley   +1 more source

Dynamic balance of myoplasmic energetics, redox state and protons in a fast‐twitch oxidative glycolytic skeletal muscle fibre

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 1840-1871, 1 March 2026.
Abstract figure legend We have developed a computational model of energy metabolism in fast‐twitch oxidative glycolytic muscle fibres. The model considers thermodynamically constrained enzyme kinetics derived from in vitro data and was validated against in vivo data from phosphorus magnetic resonance spectroscopy.
Jana Disch   +4 more
wiley   +1 more source

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