Results 191 to 200 of about 65,595 (212)
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Elevated Serum Glucose-6-Phosphate Isomerase Level in Patients with Knee Osteoarthritis
Clinical Laboratory, 2020The present study aims to analyze the serum level of glucose 6-phosphate isomerase (GPI) in patients with knee osteoarthritis (KOA) and evaluate its value in the diagnosis of KOA.One hundred patients with confirmed KOA were selected and 100 healthy people in the same period were selected as the control group.
Xiaomeng, Ji, Weiwei, Bian
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Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase
Archives of Biochemistry and Biophysics, 1988Glucose-6-phosphate isomerase exists as multiple, catalytically active isozymes which can be resolved by polyacrylamide gel electrophoresis, isoelectric focusing, and ion-exchange chromatography. GPI from bovine heart was purified to homogeneity and each of the isozymes resolved.
J K, Cini, P F, Cook, R W, Gracy
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Effect of ATP on glucose-6-phosphate isomerase from Bacillus caldotenax
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982Glucose-6-phosphate isomerase (D-glucose-6-phosphate ketol-isomerase, EC 5.3.1.9) from Bacillus caldotenax exhibits negative cooperativity in enzyme activity. Fructose 1-phosphate, fructose, 1,6-bisphosphate, phosphoenolpyruvate, 6-phosphogluconate, 3-phosphoglycerate, ATP and Pi competitively inhibit the enzyme and abolish negative cooperativity in ...
M, Takama, Y, Nosoh
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Protein disulphide isomerase assisted folding of human glucose-6-phosphate dehydrogenase
Biochemical Society Transactions, 1995Glucose 6-phosphate dehydrogenase (G6PD) plays a key role to maintain the redox state within the red cells. The molecular basis of human G6PD deficiency rely on the presence of point mutations along its 59.2 kDa subunit [l]. The intracellular active enzyme behave mostly as a homodimer.
F, Gomez-Gallego +2 more
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Modern Rheumatology, 2017
To investigate the effects of transgenic rice seeds expressing the altered peptide ligand (APL) of human glucose-6-phosphate-isomerase (hGPI325-339) in mice model of GPI-induced arthritis (GIA).We generated transgenic rice expressing T-cell epitope of hGPI325-339 and APL12 contained in the seed endosperm.
Tomoya, Hirota +11 more
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To investigate the effects of transgenic rice seeds expressing the altered peptide ligand (APL) of human glucose-6-phosphate-isomerase (hGPI325-339) in mice model of GPI-induced arthritis (GIA).We generated transgenic rice expressing T-cell epitope of hGPI325-339 and APL12 contained in the seed endosperm.
Tomoya, Hirota +11 more
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Tumori Journal, 1978
The ratios of some key enzymatic activities of carbohydrate metabolism have been measured in human tumor cytosols. The activities of whole hexokinase (low Km, EC 2.7.1.1 and high Km, EC 2.7.1.2), 6-phosphogluconate dehydrogenase (EC 1.1.1.43), glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and glucose-6-phosphate isomerase (EC 5.3.1.9) change ...
M, Miranda +5 more
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The ratios of some key enzymatic activities of carbohydrate metabolism have been measured in human tumor cytosols. The activities of whole hexokinase (low Km, EC 2.7.1.1 and high Km, EC 2.7.1.2), 6-phosphogluconate dehydrogenase (EC 1.1.1.43), glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and glucose-6-phosphate isomerase (EC 5.3.1.9) change ...
M, Miranda +5 more
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Glucose 6 phosphate isomerase as a diagnostic test in rheumatoid arthritis
Biochemical and Cellular Archives, 2022Rheumatoid arthritis (RA) a chronic auto-immune condition. is characterized by inflammation that contributes to the deterioration of joints, bones, tendons and ligaments. Glucose-6-phosphate isomerase (G6PI) is one of the autoantigens against, which RA patients develop autoantibodies that have been found to circulate in serum and in synovial fluid of ...
Kareem R. J. Alzaidi +2 more
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Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
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It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
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Amoxicillin-Induced Hemolytic Anemia in a Child with Glucose 6-Phosphate Isomerase Deficiency
Annals of Pharmacotherapy, 2010Objective:To describe the first case of amoxicillin-induced nonimmune hemolytic anemia in a child with glucose-6-phosphate isomerase (GPI) deficiency.Case Summary:A 3-year-old boy with GPI deficiency was admitted for upper respiratory tract infection and fever. The patient was treated with a standard dose of amoxicillin (50 mg/kg/day).
Francesca Rossi +6 more
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2015
A patient with combined deficiency of erythrocyte glucose phosphate isomerase (GPI) and glucose-6-phosphate dehydrogenase (G6PD) is presented. The propositus has persistent unconjugated hyperbilirubinemia. One of his two brothers exhibits the same rare enzymatic defect, but without any clinical symptoms.
I, Steiman +3 more
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A patient with combined deficiency of erythrocyte glucose phosphate isomerase (GPI) and glucose-6-phosphate dehydrogenase (G6PD) is presented. The propositus has persistent unconjugated hyperbilirubinemia. One of his two brothers exhibits the same rare enzymatic defect, but without any clinical symptoms.
I, Steiman +3 more
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