Results 191 to 200 of about 67,753 (222)
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A Novel Glucose 6-Phosphate Isomerase from Listeria monocytogenes

The Protein Journal, 2014
D-Arabinose 5-phosphate isomerases (APIs) catalyze the interconversion of D-ribulose 5-phosphate and D-arabinose 5-phosphate (A5P). A5P is an intermediate in the biosynthesis of 3-deoxy-D-manno-octulosonate (Kdo), an essential component of lipopolysaccharide, the lipopolysaccharide found in the outer membrane of Gram-negative bacteria.
Jeffrey M. Schaub   +6 more
openaire   +3 more sources

Purification and characterization of glucose-6-phosphate isomerase from Bacillus stearothermophilus

Archives of Biochemistry and Biophysics, 1971
Abstract Glucose-6-phosphate isomerase (EC 5.3.1.9) has been purified from Bacillus stearothermophilus to a state in which it is homogeneous, both ultracentrifugally and electrophoretically. The sedimentation coefficient ( s 20, w ) and molecular weight of the enzyme are 7.4S and 172,000. The enzyme exhibits a maximum activity at 70 °.
N Muramatsu, Y Noso
openaire   +2 more sources

Genetic variants in glucose-6-phosphate isomerase gene as prognosis predictors in hepatocellular carcinoma.

Clinics and Research in Hepatology and Gastroenterology, 2016
Metabolic reprogramming is an important hallmark of cancer cells, including the alterations of activity and expression of enzymes in glucose metabolism. Previous studies have demonstrated the critical role of glucise-6-phosphate isomerase (GPI) in cancer initiation, metastasis and progression.
Zhuomin Lyu   +7 more
semanticscholar   +4 more sources

Contribution of Inflammation and Bone Destruction to Pain in Arthritis: A Study in Murine Glucose‐6‐Phosphate Isomerase–Induced Arthritis

Arthritis & Rheumatology, 2019
Arthritis is often characterized by inflammation and bone destruction. This study was undertaken to investigate the contribution of inflammation and bone destruction to pain.
M. Ebbinghaus   +8 more
semanticscholar   +1 more source

Substrate specificity of a glucose-6-phosphate isomerase from Pyrococcus furiosus for monosaccharides

Applied Microbiology and Biotechnology, 2009
We purified recombinant glucose-6-phosphate isomerase from Pyrococcus furiosus using heat treatment and Hi-Trap anion-exchange chromatography with a final specific activity of 0.39 U mg(-1). The activity of the glucose-6-phosphate isomerase for L: -talose isomerization was optimal at pH 7.0, 95 degrees C, and 1.5 mM Co(2+). The half-lives of the enzyme
Ran-Young Yoon   +3 more
semanticscholar   +4 more sources

Effect of ATP on glucose-6-phosphate isomerase from Bacillus caldotenax

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
Glucose-6-phosphate isomerase (D-glucose-6-phosphate ketol-isomerase, EC 5.3.1.9) from Bacillus caldotenax exhibits negative cooperativity in enzyme activity. Fructose 1-phosphate, fructose, 1,6-bisphosphate, phosphoenolpyruvate, 6-phosphogluconate, 3-phosphoglycerate, ATP and Pi competitively inhibit the enzyme and abolish negative cooperativity in ...
Michihiro Takama, Yoshiaki Nosoh
openaire   +3 more sources

Combined Erythrocyte Phosphohexose Isomerase and Glucose-6-Phosphate Dehydrogenase Deficiency

Human Heredity, 1973
Combined erythrocyte phosphohexose isomerase (PHI) and glucose-6-phosphate dehydrogenase (G6PD) deficiency without hemolytic crisis is reported in a Thai family. The propositus (a male), heterozygous for PHI deficiency and hemizygous for G6PD deficiency, has a PHI activity of about half of the normal.
G. Flatz   +3 more
openaire   +3 more sources

Elevated Serum Glucose-6-Phosphate Isomerase Level in Patients with Knee Osteoarthritis

Clinical Laboratory, 2020
The present study aims to analyze the serum level of glucose 6-phosphate isomerase (GPI) in patients with knee osteoarthritis (KOA) and evaluate its value in the diagnosis of KOA.One hundred patients with confirmed KOA were selected and 100 healthy people in the same period were selected as the control group.
Weiwei Bian, Xiaomeng Ji
openaire   +2 more sources

Cell age dependent decay of human erythrocytes glucose-6-phosphate isomerase

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1989
Glucose-6-phosphate isomerase shows a biphasic decay pattern during red blood cell aging, which is very fast during the first part of cell's life span in circulation. This decay is not due to accumulation of inactive enzyme molecules, as shown by immunological studies, but is accompanied by the formation of secondary isozymes (i.e., chemically modified
FAZI, ANTONIO   +3 more
openaire   +4 more sources

Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders.

Arthritis & Rheumatism, 2003
OBJECTIVE Arthritis in the K/BxN mouse model results from pathogenic immunoglobulins that recognize glucose-6-phosphate isomerase (GPI), a glycolytic enzyme residing in the cytoplasm of all cells.
I. Matsumoto   +14 more
semanticscholar   +1 more source

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