Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle [PDF]
Circulation Research, 2020 Rationale: Metabolic and structural remodeling is a hallmark of heart failure. This remodeling involves activation of the mTOR (mammalian target of rapamycin) signaling pathway, but little is known on how intermediary metabolites are integrated as metabolic signals.
Anja Karlstaedt +3 more
openaire +3 more sources
Comparative Erythrocyte Metabolism in Marsupials and Monotremes [PDF]
, 1995 Concentrations of ATP and DPG, activities of 10 enzymes and the glycolytic rates were measured in the erythrocytes of 11 species of marsupials and two species of monotremes.
A.L. Parkinson +25 more
core +2 more sources
Regulatory Functions of Nilaparvata lugens GSK-3 in Energy and Chitin Metabolism
Frontiers in Physiology, 2020 Glucose metabolism is a biologically important metabolic process. Glycogen synthase kinase (GSK-3) is a key enzyme located in the middle of the sugar metabolism pathway that can regulate the energy metabolism process in the body through insulin signaling.
Yan-Juan Ding +7 more
doaj +1 more source
How are proteins reduced in the endoplasmic reticulum? [PDF]
, 2018 The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made.
Bulleid, Neil +2 more
core +2 more sources
Phylogenetic analysis of the glucose-6-phosphate isomerase gene in Trypanosoma cruzi
Experimental Parasitology, 2006 Trypanosoma cruzi, the agent of Chagas disease, has a basically clonal population structure with rare hybridization events. The species is subdivided into six "Discrete Typing Units" called DTUs I, IIa-e, distributed into two major phylogenetic lineages, T. cruzi I and II (TC I and II).
/Broutin, Hélène +4 more
openaire +4 more sources
Mechanism study of alachlor biodegradation by Paecilomycesmarquandii with proteomic and metabolomic methods [PDF]
, 2015 Alachlor is an herbicide that is widely used worldwide to protect plant crops against broadleaf weedsand annual grasses. However, due to its endocrine-disrupting activity, its application had been bannedin the European Union.
Adrian Soboń +42 more
core +1 more source
Anais da Academia Brasileira de Ciências, 2007 Trypanosoma cruzi is highly sensitive to oxidative stress caused by reactive oxygen species. Trypanothione, the parasite's major protection against oxidative stress, is kept reduced by trypanothione reductase, using NADPH; the major source of the reduced
Mariana Igoillo-Esteve +4 more
doaj +1 more source
Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. [PDF]
, 2011 Label-free LC-MS/MS-based shot-gun proteomics was used to quantify the differential protein synthesis and metabolite profiling in order to assess metabolic changes during the development of citrus fruits.
Blumwald, Eduardo +8 more
core +3 more sources
CO2-Induced Transcriptional Reorganization: Molecular Basis of Capnophillic Lactic Fermentation in Thermotoga neapolitana [PDF]
, 2020 Capnophilic lactic fermentation (CLF) is a novel anaplerotic pathway able to convert sugars to lactic acid (LA) and hydrogen using CO2 as carbon enhancer in the hyperthermophilic bacterium Thermotoga neapolitana.
Dipasquale, Laura +7 more
core +2 more sources
Reproductive strategies and genetic variability in tropical freshwater fish
Genetics and Molecular Biology, 2007 We estimated the genetic variability of nine fish species from the Brazilian upper Paraná River floodplain (Astyanax altiparanae, Hoplias malabaricus, Leporinus lacustris, Loricariichthys platymetopon, Parauchenipterus galeatus, Pimelodus maculatus ...
Maria Dolores Peres Lassala +1 more
doaj +1 more source