Results 61 to 70 of about 3,223,897 (362)

Kinetic Determination of Glucose Concentrations with Glucose Dehydrogenase [PDF]

Clinical Chemistry and Laboratory Medicine, 1977
A manual version and mechanized versions for several types of analyzers are described for the kinetic determination of glucose with glucose dehydrogenase. Results of glucose determinations with and without deproteinization of samples are discussed. The correlation of results with the hexokinase method is shown.
Rindfrey, H., Helger, R., Lang, H.
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Glucose Content of Sago Waste After Chloride Acid Pre- Treatment Hydrolysis For Bioethanol Production [PDF]

, 2015
Indonesia is a country with abundant agricultural biological resources. One of the plants as a biological source is sago. Sago processing wastes such as bark and waste about 72%.
A, Agustina LN, Djaelani, M.Anwar, Kusdyantini, Endang, Prihastanti, Erma, Sasongko, Priyo Sidik, Setyawan , Agus, Widowati, W.   +6 more
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The glucose sensor in HIT cells is the glucose transporter [PDF]

FEBS Letters, 1987
The nature of the rate‐limiting step for glucose utilization by the clonal insulin‐producing cell line HIT‐T15 has been investigated. In contrast to the situation in islets of Langerhans, we find that the HIT cell glucose metabolism is limited by the rate of entry of glucose into the cell. This is evidenced by the low rate of sugar transport and by the
Mark Stubbs, S. J. H. Ashcroft
openaire   +3 more sources

Dose–response between frequency of interruption of sedentary time and fasting glucose, the dawn phenomenon and night-time glucose in Type 2 diabetes [PDF]

, 2018
Aim: To explore the dose-response between frequency of interruption of sedentary time and basal glucose (fasting glucose, the dawn phenomenon and night-time glucose) in Type 2 diabetes.
Bailey, Bailey, Berg, Bond, Chastin, Cheema, Dempsey, Dempsey, Dunstan, Duvivier, Grant, Hawari, Healy, Helmerhorst, Honda, Johnson, Kanat, Lui, Matthews, Monnier, Monnier, Mudaliar, Nalysnyk, Paing, Porcellati, Riddle, Sardinha, Tanaka, Thomas, Tremblay   +29 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Tirzepatide, a dual GIP/GLP-1 receptor agonist, alleviates metabolic dysfunction-associated steatotic liver disease by reducing the expression of CD36 and OBP2A

Genes and Diseases
Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined by excessive hepatic lipid accumulation. This study evaluated the therapeutic effects and molecular mechanisms of tirzepatide, a dual GIP and GLP-1 receptor agonist, in treating ...
Yun Li, Wencong Sun, Hong Liu, Xiong Z. Ruan   +3 more
doaj   +1 more source

The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study

Cancer & Metabolism, 2023
Background The relationship between obesity and non-Hodgkin’s lymphoma (NHL) was controversial, which may be due to the crudeness definition of obesity based on body mass index (BMI).
Hang Dong, Honglin Guo, Jing Du, Yiping Cheng, Dawei Wang, Junming Han, Zinuo Yuan, Zhenyu Yao, Ran An, Xiaoqin Wu, Kyle L. Poulsen, Zhixiang Wang, Shanshan Shao, Xiude Fan, Zhen Wang, Jiajun Zhao   +15 more
doaj   +1 more source

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice [PDF]

, 2012
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease).
Alex J. Harper, Alison D. McNeilly, Almind, Arch, Azzu, Balleza-Tapia, Biessels, Burcelin, Butler, Cai, Cannon, Choi, Cioffi, Cole, Craft, Craft, D. Lee Hamilton, David R. Howlett, De Felice, de la Monte, de la Monte, Dominguez, Folch, Fromme, Frölich, Fukumoto, Harrison, Hassing, Ho, Huse, Ishrut Hussain, Janson, Jennifer Gallagher, John R. Speakman, Judy Latcham, Kirsten A. Bannon, Kobayashi, Kontani, Kus, LaFerla, Laura A. Burgess, Lee, Li, Lobke M. Vaanholt, Luchsinger, Luo, Mensink, Michael L.J. Ashford, Mirshamsi, Paul J. Meakin, Pietrak, Rapoport, Rivera, Roberds, Sankaranarayanan, Selman, Speakman, Steen, Tiraby, Vassar, Vassar, Vattemi, Xie   +62 more
core   +4 more sources