Results 191 to 200 of about 446,689 (286)

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Catalpol ameliorates diabetic retinal vascular endothelial injury by suppressing NLRP3 inflammasome <i>via</i> targeting METTL3-m⁶A modification. [PDF]

Int J Ophthalmol
Liu JY, Zhu JY, Xiao YF, Ge YR, Yan F, Jiang Q.   +5 more
europepmc   +1 more source

Indole‐3‐Acetic Acid Protects Bovine Hepatocytes Against Palmitic Acid‐Induced Lipid Accumulation and ER Stress Through SIRT3

Animal Research and One Health, EarlyView.
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi, Chenchen Zhao, Guiying Li, Jinxia Li, Menglin Liu, Fanrong Kong, Enzhu Li, Jie Gao, Wenqi Liao, Akos Kenez, Wenwen Gao, Yuxiang Song, Xiliang Du, Guowen Liu, Xinwei Li, Lin Lei   +15 more
wiley   +1 more source

Host metabolic responses to SARS-CoV-2 and influenza viruses: parallels and contrasts. [PDF]

Metabolomics
Terra C, Terrier O, Le Gouellec A.
europepmc   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Late Recognition of Glucose-6-Phosphate Dehydrogenase Deficiency in a 70-Year-Old Man: A Case Report. [PDF]

Cureus
Huynh J, Eisenbud L, Gutierrez R, Chuang FL, Dichter D.   +4 more
europepmc   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian, Carlos Horacio Luna‐Flores, Xu Li, Sally L. Gras, Robert E. Speight   +4 more
wiley   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source

Anesthetic Management of a Pediatric Patient With Glucose-6-Phosphate Dehydrogenase Deficiency Undergoing Emergency Rigid Esophagoscopy: A Case Report. [PDF]

Cureus
Khaliq A, Grancaric N, Girshin M, Mendonca R, Suler BJ.   +4 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source