Results 251 to 260 of about 446,689 (286)

Does Glucose-6-Phosphate Dehydrogenase Deficiency Correlate with Increased Sensitivity to Cisplatin? A Case Report and a Narrative Literature Review. [PDF]

open access: yesInt J Mol Sci
Denaro N   +10 more
europepmc   +1 more source

Sweat test in patients with glucose-6-phosphate-1-dehydrogenase deficiency

open access: yesArchives of Disease in Childhood, 2008
A false-positive sweat test in patients with deficiency of glucose-6-phosphate-1-dehydrogenase (EC 1.1.1.49; G6PD) is repeatedly reported.Sweat chloride or conductivity was measured in 11 patients with G6PD deficiency.Mean (SD) chloride level (n = 8, median age 9.2 years, range 1.9-48.5) was 18.8 (9.6 mmol/l) and, mean (SD) sodium level was 26.0 (10.0 ...
Casaulta C   +3 more
openaire   +4 more sources

Construction of an integrated enzyme system consisting azoreductase and glucose 1-dehydrogenase for dye removal

Bioresource Technology, 2013
Azo dyes are toxic and carcinogenic and are often present in industrial effluents. In this research, azoreductase and glucose 1-dehydrogenase were coupled for both continuous generation of the cofactor NADH and azo dye removal. The results show that 85% maximum relative activity of azoreductase in an integrated enzyme system was obtained at the ...
Yuyi Yang, Yuhua Zhao, Jun Wang
exaly   +3 more sources

Cloning and expression in E. coli of an organic solvent-tolerant and alkali-resistant glucose 1-dehydrogenase from Lysinibacillus sphaericus G10

Bioresource Technology, 2011
The gene gdh encoding an organic solvent-tolerant and alkaline-resistant NAD(P)-dependent glucose 1-dehydrogenase (LsGDH) was cloned from Lysinibacillus sphaericus G10 and expressed in Escherichia coli. The recombinant LsGDH exhibited maximum activity at pH 9.5 and 50 °C.
Hai-Tao, Ding   +5 more
exaly   +3 more sources

Characterization of the low-temperature activity of Sulfolobus tokodaii glucose-1-dehydrogenase mutants

Journal of Bioscience and Bioengineering, 2014
Thermophilic enzymes are potentially useful for industrial processes because they are generally more stable than are mesophilic or psychrophilic enzymes. However, a crucial drawback for their use in such processes is that most thermophilic enzymes are nearly inactive at moderate and low temperatures.
Taisuke, Sugii   +5 more
openaire   +2 more sources

Characterization of a robust glucose 1-dehydrogenase, SyGDH, and its application in NADPH regeneration for the asymmetric reduction of haloketone by a carbonyl reductase in organic solvent/buffer system

Process Biochemistry, 2020
Abstract To realize coenzyme regeneration in the reduction of haloketones, a codon-optimized gene Sygdh encoding glucose 1-dehydrogenase (SyGDH) was synthesized based on the putative GDH gene sequence (Ta0897) in Thermoplasma acidophilum genomic DNA, and expressed in E. coli BL21(DE3).
Die Hu   +6 more
openaire   +1 more source

Significant improvement of thermal stability of glucose 1-dehydrogenase by introducing disulfide bonds at the tetramer interface

Enzyme and Microbial Technology, 2013
Rational design was applied to glucose 1-dehydrogenase (LsGDH) from Lysinibacillus sphaericus G10 to improve its thermal stability by introduction of disulfide bridges between subunits. One out of the eleven mutants, designated as DS255, displayed significantly enhanced thermal stability with considerable soluble expression and high specific activity ...
Haitao, Ding   +6 more
openaire   +2 more sources

Human Hexose-6-phosphate Dehydrogenase (Glucose 1-Dehydrogenase) Encoded at 1p36: Coding Sequence and Expression

Blood Cells, Molecules, and Diseases, 1999
Using the published protein sequence from a rabbit microsomal glucose-6-phosphate dehydrogenase G6PD we have isolated and sequenced a cDNA clone coding for its human equivalent, which is also known as hexose-6-phosphate dehydrogenase (H6PD) and glucose dehydrogenase.
P J, Mason   +5 more
openaire   +2 more sources

Structure‐guided mutagenesis for the improvement of substrate specificity of Bacillus megaterium glucose 1‐dehydrogenase IV

The FEBS Journal, 2012
Bacillus megaterium IAM 1030 (Bacillus sp. JCM 20016) possesses four d‐glucose 1‐dehydrogenase isozymes (BmGlcDH‐I, ‐II, ‐III and ‐IV) that belong to the short‐chain dehydrogenase/reductase superfamily. The BmGlcDHs are currently used for a clinical assay to examine blood glucose levels.
Taiki, Nishioka   +3 more
openaire   +2 more sources

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