Results 171 to 180 of about 680,483 (305)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Helicobacter pylori infection impairs glucose homeostasis through gut microbiota dysbiosis. [PDF]

BMC Microbiol
Chen H, Wang Z, Su W, Li S, Ye Q, Zhang G, Zhou X.   +6 more
europepmc   +1 more source

In vivo measurement of the rate constant of liver handling of glucose and glucose uptake by insulin-dependent tissues, using a mathematical model for glucose homeostasis in diabetic rats

, 2017
Mercedes Lombarte, Maela Lupo, L. Fina Brenda, Germán Campetelli, Afonso Rabel Buzalaf Marília, Marta Basualdo, Alfredo Rigalli   +6 more
openalex   +2 more sources

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis [PDF]

, 2011
Maria M. Mihaylova, Debbie S. Vasquez, Kim Ravnskjær, Pierre‐Damien Denechaud, Ruth T. Yu, Jacqueline G. Alvarez, Michael Downes, Ronald M. Evans, Marc Montminy, Reuben J. Shaw   +9 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting Glucokinase. [PDF]

FASEB J
Miao Y, Meng Z, Chen S, Li X, Fang T, Deng X, Sun B, Chen L.   +7 more
europepmc   +1 more source

Rho GTPases – Emerging Regulators of Glucose Homeostasis and Metabolic Health

, 2019
Lisbeth L. V. Møller, Amira Klip, Lykke Sylow   +2 more
openalex   +2 more sources

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

Hepatic Glucocorticoid Receptor Action and Glucose Homeostasis.

Endocr Rev
Chang M, Wang JC.
europepmc   +1 more source

Deletion of C3G in hepatocytes impairs full liver maturation and alters glucose homeostasis. [PDF]

Cell Death Dis
Palao N, Mancebo J, Baquero C, Iniesta-González M, Cueto-Remacha M, Rodrigo-Faus M, Gutierrez-Uzquiza A, Bragado P, Cuesta ÁM, Sánchez A, Guerrero C, Porras A.   +11 more
europepmc   +1 more source