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A protocol for studying glucose homeostasis and islet function in mice
Summary: Glucose tolerance test and glucose stimulated insulin secretion are important measures to determine glucose homeostasis and islet function and assess diabetes.
Dana Al Rijjal, Michael B. Wheeler
doaj
The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]
The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M.+10 more
core +2 more sources
Pancreatic regulation of glucose homeostasis [PDF]
In order to ensure normal body function, the human body is dependent on a tight control of its blood glucose levels. This is accomplished by a highly sophisticated network of various hormones and neuropeptides released mainly from the brain, pancreas, liver, intestine as well as adipose and muscle tissue.
Bingbing Wu+3 more
openaire +3 more sources
The capability of carbohydrate utilization in fish is limited compared to mammals. It has scientific and practical significance to improve the ability of fish to use carbohydrates. The efficiency of dietary carbohydrate utilization varies among fish with
Anran Wang+6 more
doaj +1 more source
Glycolysis Regulation to Maintain Blood Glucose homeostasis
Carbohydrates are the major source of energy for the living cells, they are the first cellular constituents that synthesized during photosynthesis from carbon dioxide and water by green plants through absorption of sun light.
Karzan Jalal Salih+2 more
doaj +1 more source
GLUT2, glucose sensing and glucose homeostasis [PDF]
The glucose transporter isoform GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms.
openaire +4 more sources
Glucose Homeostasis, Diabetes Mellitus, and Gender-Affirming Treatment
The transgender (trans) population includes individuals with gender identities more fittingly aligned with the opposite sex or with an alternative that transcends the classical dipole of male/female.
Charalampos Milionis+3 more
doaj +1 more source
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells [PDF]
ATP-sensitive potassium channels (K(ATP) channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, K(ATP) channels are essential for coupling glucose metabolism to insulin secretion.
Conway, Hannah+8 more
core +2 more sources
Regulation of Glucose Homeostasis by Glucocorticoids [PDF]
Glucocorticoids are steroid hormones that regulate multiple aspects of glucose homeostasis. Glucocorticoids promote gluconeogenesis in liver, whereas in skeletal muscle and white adipose tissue they decrease glucose uptake and utilization by antagonizing insulin response.
Kuo, Taiyi+3 more
openaire +6 more sources
High protein diets are known to improve metabolic parameters including adiposity and glucose homeostasis. Here the authors demonstrate that preabsorptive upper small intestinal protein-sensing mechanisms mediated by peptide transporter 1 improve glucose ...
Helen J. Dranse+6 more
doaj +1 more source