Results 41 to 50 of about 1,612,298 (197)

GLUT2, glucose sensing and glucose homeostasis [PDF]

Diabetologia, 2014
The glucose transporter isoform GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms.
openaire   +3 more sources

Glucose tolerance and weight loss in obese women with obstructive sleep apnea. [PDF]

PLoS ONE, 2013
BACKGROUND: The association of obstructive sleep apnea (OSA) with glucose intolerance and the beneficial effect of lifestyle intervention have been poorly investigated in women particularly before menopausal status.
Luisa Gilardini, Carolina Lombardi, Gabriella Redaelli, Luciana Vallone, Andrea Faini, Paola Mattaliano, Gianfranco Parati, Cecilia Invitti   +7 more
doaj   +1 more source

Rosiglitazone RECORD study: glucose control outcomes at 18 months. [PDF]

, 2007
AIMS: To compare glucose control over 18 months between rosiglitazone oral combination therapy and combination metformin and sulphonylurea in people with Type 2 diabetes.
Beck-Nielsen, H, Jones, N P, Home, PD, Hanefeld, M, Gomis, R, Pocock, SJ, Pocock, S J, Komajda, M, Jones, NP, Study Group, RECORD, Curtis, P, RECORD Study Group, Home, P D   +12 more
core   +1 more source

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. [PDF]

, 2008
OBJECTIVE Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related ...
Nogueiras, Ruben, Klein, Marcella, Liposits, Zsolt, Tschöp, Matthias H., Watanabe, Masahiko, Rohner-Jeanrenaud, Francoise, Wittmann, Gábor, Veyrat-Durebex, Christelle, Tschöp, Johannes, Fekete, Csaba, Reizes, Ofer, Woods, Stephen C., Suchanek, Paula M., Caldwell, Charles   +13 more
core   +3 more sources

Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians : ADCY5 and GLIS3 variants may predispose to type 2 diabetes [PDF]

, 2011
Background: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly associated with fasting glucose, some of which were also associated with type 2 diabetes.
Hydrie, MZI, Simon D. Rees, Abdul Basit, Hydrie M. Zafar I., Shera, A. Samad, Barnett, Anthony, Shera A. Samad, M. Zafar I. Hydrie, Basit, A, Basit Abdul, Anthony H Barnett, J. Paul O'Hare, Kumar Sudhesh, Sudhesh Kumar, Rees, Simon D., Rees, Simon, Kelly, M. Ann, Shera, AS, Kelly, Marilyn, A Samad Shera, Basit, Abdul, O'Hare J. Paul, Rees Simon D., J Paul O'Hare, A. Samad Shera, O'Hare, JP, Anthony H. Barnett, Kumar, Sudhesh, M. Ann Kelly, Kelly M. Ann, Hydrie, M. Zafar I., Simon D Rees, Barnett, A. H., Kumar, S, M Zafar I Hydrie, O'Hare, J. Paul, Barnett Anthony H., M Ann Kelly   +37 more
core   +2 more sources

Glucose Homeostasis [PDF]

Proceedings of the Royal Society of Medicine, 1968
S J, Ashcroft, P J, Randle
  +18 more sources

TRPV1 neurons regulate β-cell function in a sex-dependent manner

Molecular Metabolism, 2018
There is emerging evidence to support an important role for the transient receptor potential vanilloid type 1 (TRPV1) sensory innervation in glucose homeostasis.
Joey Bou Karam, Weikang Cai, Rowaida Mohamed, Tianwen Huang, Lingqiong Meng, Erica Paige Homan, Ercument Dirice, C. Ronald Kahn, Abdelfattah El Ouaamari   +8 more
doaj   +1 more source

Rho Family GTPases and Rho GEFs in Glucose Homeostasis

Cells, 2021
Dysregulation of glucose homeostasis leading to metabolic syndrome and type 2 diabetes is the cause of an increasing world health crisis. New intriguing roles have emerged for Rho family GTPases and their Rho guanine nucleotide exchange factor (GEF ...
Polly A. Machin, Elpida Tsonou, David C. Hornigold, Heidi C. E. Welch   +3 more
doaj   +1 more source

Critical illness-induced dysglycaemia : diabetes and beyond [PDF]

, 2010
Type 2 diabetes has reached epidemic proportions in many parts of the world. The disease is projected to continue to increase and double within the foreseeable future.
Ann M Sheehy, Sheehy, Ann M., Vincent, J.-L. (Jean-Louis), Fang Smith, Vincent, J. L., Jean-Louis Vincent, Coursin, Douglas B., Smith, F. Gao (Fang Gao), Sheehy, A.M. (Ann M.), Douglas B Coursin, Smith, F.G. (Fang G.), Coursin, D.B. (Douglas B.)   +11 more
core   +1 more source

Physiological and therapeutic regulation of glucose homeostasis by upper small intestinal PepT1-mediated protein sensing

Nature Communications, 2018
High protein diets are known to improve metabolic parameters including adiposity and glucose homeostasis. Here the authors demonstrate that preabsorptive upper small intestinal protein-sensing mechanisms mediated by peptide transporter 1 improve glucose ...
Helen J. Dranse, T. M. Zaved Waise, Sophie C. Hamr, Paige V. Bauer, Mona A. Abraham, Brittany A. Rasmussen, Tony K. T. Lam   +6 more
doaj   +1 more source