Results 51 to 60 of about 1,612,298 (197)

Astrocytes in the nucleus of the solitary tract are activated by low glucose or glucoprivation: evidence for glial involvement in glucose homeostasis.

Frontiers in Neuroscience, 2013
Glucose homeostasis is maintained through interplay between central and peripheral control mechanisms which are aimed at storing excess glucose following meals and mobilizing these same stores during periods of fasting. The nucleus of the solitary tract (
David Harry McDougal, Gerlinda E Hermann, Richard C Rogers   +2 more
doaj   +1 more source

SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

Scientific Reports, 2022
Modelling insulin-glucose homeostasis may provide novel functional insights. In particular, simple models are clinically useful if they yield diagnostic methods.
Johannes W. Dietrich, Riddhi Dasgupta, Shajith Anoop, Felix Jebasingh, Mathews E. Kurian, Mercy Inbakumari, Bernhard O. Boehm, Nihal Thomas   +7 more
doaj   +1 more source

Hepatic Dyrk1b impairs systemic glucose homeostasis by modulating Wbp2 expression in a kinase activity-dependent manner

Heliyon
Patients with gain-of-function mutations of Dyrk1b have higher fasting blood glucose (FBG) levels. However, the role of Dyrk1b in glucose metabolism is not fully elucidated.
Lianju Li, Yaoyu Zou, Chongrong Shen, Na Chen, Muye Tong, Ruixin Liu, Jiqiu Wang, Guang Ning   +7 more
doaj   +1 more source

The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis

eLife, 2021
Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is involved in multiple biological functions in cell development, differentiation, and transcriptional regulation. Tet1 deficient mice display the defects of murine glucose metabolism. However,
Chunbo Zhang, Tianyu Zhong, Yuanyuan Li, Xianfeng Li, Xiaopeng Yuan, Linlin Liu, Weilin Wu, Jing Wu, Ye Wu, Rui Liang, Xinhua Xie, Chuanchuan Kang, Yuwen Liu, Zhonghong Lai, Jianbo Xiao, Zhixian Tang, Riqun Jin, Yan Wang, Yongwei Xiao, Jin Zhang, Jian Li, Qian Liu, Zhongsheng Sun, Jianing Zhong   +23 more
doaj   +1 more source

Pancreatic regulation of glucose homeostasis [PDF]

Experimental & Molecular Medicine, 2016
In order to ensure normal body function, the human body is dependent on a tight control of its blood glucose levels. This is accomplished by a highly sophisticated network of various hormones and neuropeptides released mainly from the brain, pancreas, liver, intestine as well as adipose and muscle tissue.
Röder, Pia V, Wu, Bingbing, Liu, Yixian, Han, Weiping   +3 more
openaire   +2 more sources

Role of fibroblast growth factor 19 in the control of glucose homeostasis

, 2012
PURPOSE OF REVIEW: Fibroblast growth factor 19 (FGF19) is a postprandial hormone released from the small intestine. FGF19 improves glucose tolerance when overexpressed in mice with impaired glucose tolerance or diabetes. This review summarizes the recent
Schaap, F.G., Schaap, Frank G.
core   +1 more source

Estudo da atividade biológica de Baccharis articulata, Musa x paradisiaca e rutina na homeostasia da glicose em modelos experimentais in vivo e in vitro [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaA insulina é o principal hormônio anabólico responsável pelo controle da captação, utilização e armazenamento dos nutrientes ...
Kappel, Virginia Demarchi
core  

A single extra copy of Down syndrome critical region 1–4 results in impaired hepatic glucose homeostasis

Molecular Metabolism, 2019
Objectives: During fasting, hepatic gluconeogenesis is induced to maintain energy homeostasis. Moreover, abnormal dysregulation of hepatic glucose production is commonly observed in type 2 diabetes.
Dong Soo Seo, Gia Cac Chau, Kwan-Hyuck Baek, Sung Hee Um   +3 more
doaj   +1 more source

A parsimonious model of blood glucose homeostasis.

PLOS Digital Health, 2022
The mathematical modelling of biological systems has historically followed one of two approaches: comprehensive and minimal. In comprehensive models, the involved biological pathways are modelled independently, then brought together as an ensemble of ...
Eric Ng, Jaycee M Kaufman, Lennaert van Veen, Yan Fossat   +3 more
doaj   +1 more source

A closed-loop multi-level model of glucose homeostasis. [PDF]

PLoS ONE, 2018
The pathophysiologic processes underlying the regulation of glucose homeostasis are considerably complex at both cellular and systemic level. A comprehensive and structured specification for the several layers of abstraction of glucose metabolism is ...
Cansu Uluseker, Giulia Simoni, Luca Marchetti, Marco Dauriz, Alice Matone, Corrado Priami   +5 more
doaj   +1 more source