CFTR Deficiency Affects Glucose Homeostasis via Regulating GLUT4 Plasma Membrane Transportation
Cystic Fibrosis (CF) is an autosomal recessive disorder caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. CF-related diabetes (CFRD) is one of the most prevalent comorbidities of CF.
Junzhong Gu +4 more
doaj +1 more source
Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Steffens, A.B. +11 more
core +1 more source
Links between Thyroid Disorders and Glucose Homeostasis [PDF]
Thyroid disorders and diabetes mellitus often coexist and are closely related. Several studies have shown a higher prevalence of thyroid disorders in patients with diabetes mellitus and vice versa. Thyroid hormone affects glucose homeostasis by impacting
Young Sil Eom +2 more
doaj +1 more source
Low-carbohydrate diets affect energy balance and fuel homeostasis differentially in lean and obese rats [PDF]
In parallel with increased prevalence of overweight people in affluent societies are individuals trying to lose weight, often using low-carbohydrate diets.
van Dijk, G. +12 more
core +2 more sources
Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
R. Jund +7 more
core +1 more source
Objectives: Hepatokines are proteins secreted by the liver that impact the functions of the liver and various tissues through autocrine, paracrine, and endocrine signaling.
Mathilde Mouchiroud +23 more
doaj +1 more source
Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis [PDF]
Peer ...
Welch, A +83 more
core +2 more sources
The nuclear receptor hepatocyte nuclear factor 4alpha (HNF4α) plays a critical role in the regulation of metabolic homeostasis, including glucose homeostasis.
Yuhan Bi, Youya Wang, Wen Xie
doaj +1 more source
Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background. [PDF]
Type 2 Diabetes is a global health burden and based on current estimates will become an even larger problem in the future. Developing new strategies to prevent and treat diabetes is a scientific challenge of high priority. The stomach hormone ghrelin has
Henriette Kirchner +5 more
doaj +1 more source
The Interaction of Insulin and Pituitary Hormone Syndromes
Pituitary hormone axes modulate glucose metabolism and exert direct or indirect effects on insulin secretion and function. Cortisol and growth hormone are potent insulin-antagonistic hormones.
Marie Helene Schernthaner-Reiter +3 more
doaj +1 more source

