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The Role of the Nuclear Receptor FXR in Arsenic-Induced Glucose Intolerance in Mice
Toxics, 2023 Inorganic arsenic in drinking water is prioritized as a top environmental contaminant by the World Health Organization, with over 230 million people potentially being exposed. Arsenic toxicity has been well documented and is associated with a plethora of
Yifei Yang +3 more
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Glucose intolerance and dementia
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2011 耐糖能障害―肥満・メタボリックシンドローム・糖尿病―は，認知障害や認知症のリスクファクターである．医師を対象とした認知症診療に関するアンケート調査では，生活習慣病を有する高齢者では，認知症が見逃されやすいことが示された．認知症の早期発見には，医師のみならずケアスタッフの教育や認知症を積極的に疑うことが重要と考えられる．高齢者糖尿病の脳を守るために，代謝性脳症予防の視点からは，随時血糖を270 mg/dl 以下に管理することは合理的な目標値と考えられる．アルツハイマー型認知症の動物実験モデルでも，神経細胞障害を抑制するために，高血糖・低血糖，急峻な血糖変動を避けることが重要であった．今後，アミロイド神経病変の抑制，ADLの維持という視点から，更なる具体的な血糖管理目標値が提唱されるべきである．
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Inflammation and Glucose Intolerance [PDF]
Diabetes Care, 2004 OBJECTIVE—Increased leukocyte count is a marker of inflammation that has been associated with the development of type 2 diabetes in prospective studies. Although gestational diabetes mellitus (GDM) and type 2 diabetes share certain pathophysiological mechanisms, few studies have examined inflammation and risk of GDM.
Myles Wolf +6 more
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Primary care for diabetes in HIV-infected patients [PDF]
, 2007 Diabetes mellitus (DM) is a common disorder affecting individuals of all ages. Similar to general population, DM can also be seen in HIV infected cases.
Wiwanitkit, Viroj
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt +9 more
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PLoS ONE, 2022 The aim of the present study was to evaluated hemoglobin A1c (HbA1c), the hemoglobin glycation index (HGI), and triglyceride and glucose (TG) index as predictive indicators for low feed intake in lactating sows due to glucose intolerance. Cactus (Opuntia
Rosa Elena Pérez +5 more
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Inhibition of central insulin-receptor signaling by S961 causes hyperglycemia and glucose intolerance in rats [PDF]
, 2011 Genetic ablation studies confirmed the role of central insulin-receptor signaling (CIRS) in fuel metabolism. However, the need to examine the role of CIRS in glucose homeostasis under normal physiological condition is indispensable, as insulin affects ...
Ajit Vikram, Gopabandhu Jena
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Animal Models and Experimental Medicine, EarlyView.The experimental type 2 diabetes model in rats induced by streptozotocin and nicotinamide showed that silver nanoparticles synthesized from lemongrass extract modulate blood glucose, water and food intake, and enhance antioxidant enzyme synthesis and weight gains.
Milad Faraji +6 more
wiley +1 more source
Characterization of pancreatic islets in two selectively bred mouse lines with different susceptibilities to high-fat diet-induced glucose intolerance. [PDF]
PLoS ONE, 2014 Hereditary predisposition to diet-induced type 2 diabetes has not yet been fully elucidated. We recently established 2 mouse lines with different susceptibilities (resistant and prone) to high-fat diet (HFD)-induced glucose intolerance by selective ...
Mototsugu Nagao +9 more
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Glucose Intolerance in Pregnancy and Offspring Obesity in Late Adolescence [PDF]
, 2022 Cole D. Bendor +12 more
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