Results 81 to 90 of about 2,150,903 (254)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Blood glucose at admission, glycemic variability, and in-hospital mortality.

Blood glucose at admission, glycemic variability, and in-hospital mortality.
Weifang Huang (18190367), Junhua Chen (1659316), Nan Liang (395829)   +2 more
core   +1 more source

Initiation of Insulin Degludec in Chinese Hospitalized Patients with Type 2 Diabetes – A Single Center’s Experience

Diabetes, Metabolic Syndrome and Obesity
Wei Qiang,1,* Mengyi Li,1,2,* Sucai Song,1,3 Ruiqing Dong,1 Tongxin Zhang,1 Xuna Kou,1 Yuan Wu,1 Zhaoxu Wang,1,4 Jiayue Liu,1 Juan Liu,1 Yi Wang,1 Xiaoyan Wu,1 Bingyin Shi,1 Hui Guo1 1Department of Endocrinology and Metabolism, the First ...
Qiang W, Li M, Song S, Dong R, Zhang T, Kou X, Wu Y, Wang Z, Liu J, Liu J, Wang Y, Wu X, Shi B, Guo H   +13 more
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

The glycemic variability at different blood glucose levels at admission.

The glycemic variability at different blood glucose levels at admission.
Weifang Huang (18190367), Junhua Chen (1659316), Nan Liang (395829)   +2 more
core   +1 more source

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes [PDF]

, 2014
Aims/hypothesis: Impaired glucose uptake in skeletal muscle is an important contributor to glucose intolerance in type 2 diabetes. The aspartate protease, beta-site APP-cleaving enzyme 1 (BACE1), a critical regulator of amyloid precursor protein (APP ...
Hamilton, D. Lee, Montagut , Gemma, Meakin, Paul J., Susan M. Jalicy, Meakin, PJ, D. Lee Hamilton, Dawn Bestow, Bestow, D, Hamilton, DL, Montagut, G, Michael L. J. Ashford, Jalicy, Susan M., Findlay, John A., Jalicy, SM, Ashford, MLJ, Ashford, Michael L. J.; id_orcid, Montagut, Gemma, John A. Findlay, Gemma Montagut, Meakin, Paul J, Ashford, Michael L J, Bestow, Dawn, Findlay, John A, Jalicy, Susan M, Hamilton, David Lee, Findlay, JA, Paul J. Meakin   +26 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Lifestyle, glucose regulation and the cognitive effects of glucose load in middle-aged adults [PDF]

, 2008
Interventions aimed at improving glucose regulatory mechanisms have been suggested as a possible source of cognitive enhancement in the elderly. In particular, previous research has identified episodic memory as a target for facilitation after either ...
Riby, Leigh, McLaughlin, J, Riby, Deborah, Riby, LM, Riby, DM, McLaughlin, Jennifer   +5 more
core   +1 more source

Impact of antenatal corticosteroid exposure on glycemic control in preterm infants assessed by continuous glucose monitoring: preliminary results from a single center study

Frontiers in Endocrinology
BackgroundAntenatal corticosteroids (ACS) are routinely administered to women at risk of preterm delivery to improve neonatal respiratory outcomes. However, ACS exposure has been associated with neonatal hypoglycemia, and its impact on overall glycemic ...
Irene Bonato, Andrea Calandrino, Samuele Caruggi, Marcella Battaglini, Francesco Vinci, Gaia Cipresso, Carolina Montobbio, Chiara Andreato, Giorgia Brigati, Luca Antonio Ramenghi, Luca Antonio Ramenghi   +10 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source