Results 11 to 20 of about 103,359 (263)

Coumaroyl and feruloyl flavonoid glycosides from the male flowers of Ginkgo biloba L. and their inhibitory activity against α-glucosidase

open access: yes, 2021
Four flavonoid glycosides containing coumaroyl or feruloyl groups were isolated from the male flowers of Ginkgo biloba L., and compounds 3 and 4 were identified as novel compounds.
Wei-Dong Zhu (1478668)   +4 more
core   +1 more source

Cafestol analogues from Coffea canephora: in vitro inhibition and molecular docking to α-glucosidase

open access: yes, 2022
A new cafestol-type diterpenoid, 5β-hydroxy-2-oxocafestol named coffecanepholide C (1) along with three known diterpenoids including cafestol (2), tricalysiolide A (3) and atractyligenin (4) were identified from the Coffea canephora trunks collected at ...
Thi Anh Tuyet Nguyen (9558826)   +3 more
core   +1 more source

Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase

open access: yes, 2022
Pompe disease is an inherited metabolic disorder due to the deficiency of the lysosomal acid α-glucosidase (GAA). The only approved treatment is enzyme replacement therapy with the recombinant enzyme (rhGAA).
Roberta Iacono (4610482)   +12 more
core   +1 more source

Phytoconstituents of Endiandra kingiana; antidiabetic effects and molecular docking studies on alpha-amylase and alpha-glucosidase

open access: yes, 2023
Phytochemical investigation on the bark of E. kingiana plant afforded ten compounds, including six polyketides namely kingianin A 1, kingianin B 2, kingianin E 3, kingianin F 4, kingianin K 5 and kingianin L 6, three endiandric acids; kingianic acid A 7,
Mohamad Hafizi Abu Bakar (10528601)   +9 more
core   +1 more source

N‑Glycosylation and Gaucher Disease Mutation Allosterically Alter Active-Site Dynamics of Acid-β-Glucosidase

open access: yes, 2020
Allosteric regulations of the catalytic activity of enzymes in cellular processes remain poorly understood. Here, we advance the understanding of these critical processes by providing insights into the allosteric mechanism of acid-β-glucosidase, an ...
Mohamed Momin   +7 more
core   +1 more source

Investigation of the Germination of Barley and Wheat Grains with a Design of Experiments for the Production of Hydrolases

open access: yesFood Technology and Biotechnology, 2015
The production of hydrolases from cereals has been examined in order to investigate food-derived enzymes as an alternative source to microbial enzymes for the use in food processes.
Bertolt Kranz   +3 more
doaj   +1 more source

You Want it Sweeter: How Glycosylation Affects Plant Response to Oxidative Stress

open access: yesFrontiers in Plant Science, 2020
Oxidative stress is a cellular threat which puts at risk the productivity of most of crops valorized by humankind in terms of food, feed, biomaterial, or bioenergy.
Marc Behr   +3 more
doaj   +1 more source

Eukaryotic Expression and Purification Technology of Glucosidase in Pichia Pastoris

open access: yeseFood, 2021
Glucosidase is one of the most important hydrolases in the carbohydrate metabolism pathway in human body. It is noteworthy that glucosidase was raising high attention in numerous researches, attributed to its functional values and biological activities ...
Weijie Zhou, Dongsheng Yao, Weibin Bai
doaj   +1 more source

Study on the Synthesis and Biological Activities of N-Alkylated Deoxynojirimycin Derivatives with a Terminal Tertiary Amine

open access: yesActa Chimica Slovenica, 2020
A series of N-alkylated deoxynojirimycin (DNJ) derivatives connected to a terminal tertiary amine at the alkyl chains of various lengths were prepared.
Lin Wang, Zhijie Fang
doaj   +1 more source

An In-Depth Study on the Metabolite Profile and Biological Properties of Primula auriculata Extracts: A Fascinating Sparkle on the Way from Nature to Functional Applications

open access: yesAntioxidants, 2022
The biological activity of the aerial part and rhizomes of Primula auriculata were assessed for the first time. The biological activities (antioxidant properties, enzyme inhibition, and AGE inhibition) as well as the phenolic and flavonoid contents of ...
Inci Kurt-Celep   +9 more
doaj   +1 more source

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