Results 21 to 30 of about 7,863 (214)

Structural characterization of the bglH gene encoding a beta-glucosidase-like enzyme in an endophytic Bacillus pumilus strain

Genetics and Molecular Biology, 2007
A beta-glucosidase-like enzyme-encoding gene (bglH) of an endophytic Bacillus pumilus strain (CL16) was cloned using a shotgun genomic library constructed in Escherichia coli. The nucleotide sequence of the entire cloned fragment (2484 bp) was determined
Andréa C. Bogas, Maria Angelica E. Watanabe, Aneli Barbosa, Laurival A. Vilas-Boas, Ana C. Bonatto, Robert Dekker, Emanuel M. Souza, Maria Helena P. Fungaro   +7 more
doaj   +1 more source

Antidiabetic potential of methanol extracts from leaves of Piper umbellatum L. and Persea americana Mill.

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To determine inhibitory activity of methanolic leaf extract of Piper umbellatum and Persea americana (P. americana) (traditionally used in Cameroon against diabetes) on α -glucosidase, β -glucosidase, maltase-glucoamylase, aldose reductase and
Guy Sedar Singor Njateng, Sumera Zaib, Larissa Yetenge Chimi, Cesaire Feudjio, Raymond Simplice Mouokeu, Donatien Gatsing, Jules-Roger Kuiate, Ezekiel Adewole, Jamshed Iqbal   +8 more
doaj   +1 more source

In vitro and in vivo anti-hyperglycemia effects of extract of Faloak (Sterculia quadrifida R.Br.) leaves

Pharmaciana
Despite the availability of various conventional treatments, diabetes mellitus remains a serious global health concern with an increasing prevalence. This trend underscores the need to explore potential natural alternatives.
Velia Andrestia Dias, Laurenza Celine Dinanda, Charles Conrad Rambung, Maria Dewi Puspitasari Tirtaningtyas Gunawan Puteri, Jeffry Julianus, Phebe Hendra   +5 more
doaj   +1 more source

Comparison of the glucooligosaccharide profiles produced from maltose by two different transglucosidases from Aspergillus niger [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2010
Prebiotic isomaltooligosaccharide (IMO) preparations contain α-D-glucooligosaccharides and their structure is the key factor for their prebiotic potential.
Goffin, D., Wathelet, B., Blecker, C., Deroanne, C., Malmendier, Y., Paquot, M.   +5 more
doaj  

A Novel Soy Isoflavone Derivative, 3′-Hydroxyglycitin, with Potent Antioxidant and Anti-α-Glucosidase Activity

Plants, 2022
This study demonstrated the enzymatic hydroxylation of glycitin to 3′-hydroxyglycitin, confirming the structure by mass and nucleic magnetic resonance spectral analyses.
Jiumn-Yih Wu, Tzi-Yuan Wang, Hsiou-Yu Ding, Chuan-Che Lee, Te-Sheng Chang   +4 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Potential of Scorpion (Scorpiops pseudomonatus) Venom in Diabetes Therapy: A Study on α-Amylase and α-Glucosidase Inhibition [PDF]

Journal of Liaquat National Hospital
Background: The increasing number of diabetes mellitus patients and the complications of its treatment using chemical medicine have made it necessary to look for new treatment options that can control blood glucose levels.
Syed Asif Nawaz, Hossein Vatanpour, Shehwar Ahmed, Mohammad Assad, Aftab Alam   +4 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources

Fractionation of Dioscorea bulbifera bulbil protein, its antioxidative potential and inhibitory effects on Carbohydrate-hydrolyzing enzymes [PDF]

Trends in Pharmaceutical Sciences
The study fractionated Dioscorea bulbifera bulbil proteins, determined the fractions inhibitory potential against α-amylase and α-glucosidase activity, and evaluated their antioxidative activity in-vitro.
Oludele ODEKANYIN, Eniola BADMUS, Deborah Akinyemi   +2 more
doaj   +1 more source