Solacanin C, a new pregnane steroid from <i>Solanum torvum</i> fruits: structural elucidation, potent α-glucosidase inhibition, and <i>in silico</i> ADMET profiling. [PDF]
Le TH +7 more
europepmc +1 more source
Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis
ABSTRACT Kidney disease is a major microvascular complication of diabetes, affecting approximately 40% of individuals with diabetes, and is a leading cause of end‐stage renal disease. Besides the functional consequences of hyperglycemia; hemodynamic alterations are well understood.
Deenadhayalan Ashok +3 more
wiley +1 more source
Discovery of 4-aminochalcone-based dual α-glucosidase and aldose reductase inhibitors: <i>in vitro</i>, <i>in vivo</i>, and <i>in silico</i> studies. [PDF]
Mughal EU +9 more
europepmc +1 more source
ABSTRACT Aims Weight loss by laparoscopic sleeve gastrectomy (LSG) compared to medical weight loss (low‐calorie diet: LCD) ameliorates diabetes and metabolic dysfunction‐associated steatotic liver disease (MASLD). We aimed to evaluate changes in liver pathology 1‐year after LSG and their associations with metabolic factors in Japanese participants with
Daiki Matsubara +11 more
wiley +1 more source
Organ-Specific Phenolic Profiles, Antioxidant Capacity, and Enzyme-Inhibitory Activities of the Turkish Endemic <i>Origanum bilgeri</i>. [PDF]
Karakus Z, Sarikurkcu C.
europepmc +1 more source
Abstract Green macroalgae from the Ulva genus are rich in polysaccharides of interest, including ulvan, starch, and cellulose. However, their content and structure are impacted by environmental factors, which poses challenges for industrial applications, especially in the context of climate change.
Julie Grivotte, Zoë A. Popper
wiley +1 more source
Plant by-products as a valuble source of natural antiglycemic compounds: Economic aspects and alternative raw material sources. [PDF]
Đorđević T +3 more
europepmc +1 more source
ABSTRACT The urgent need for renewable resources has increased the interest in woody biomass to manufacture bio‐based products. However, lignin recalcitrance limits the enzymatic conversion of wood into fermentable sugars, posing a major challenge for biomass deconstruction.
Nette De Ridder +9 more
wiley +1 more source
HighHydrostaticPressure-Assisted Curing of <i>Vanilla planifolia</i>: Effects on Moisture Loss, Phenolic Content, Enzyme Activities, and Antioxidant Capacity. [PDF]
Navarro-Baez JE +2 more
europepmc +1 more source
Metabolic Rewiring of the Shikimate Pathway Enables Rose‐Scented Rice
ABSTRACT Rice fragrance is a key determinant of grain quality, yet the aroma profile of cultivated rice is highly uniform and largely dominated by the popcorn‐like compound 2‐acetyl‐1‐pyrroline. Here we expanded the aromatic repertoire of rice by engineering a rose‐like fragrance through reconstruction of the phenylalanine‐derived 2‐phenylethanol (2‐PE)
Xiaoqing Cui +11 more
wiley +1 more source

