Results 221 to 230 of about 103,359 (263)

Plasma FGF21 is associated with intracranial atherosclerotic stenosis in patients with type 2 diabetes mellitus. [PDF]

Front Neurol
Wang Q, Zhang X, Xiao Y, Zhou S, Liu Y, Xie C, Chen J, Wu S, Kong M, Xu H.   +9 more
europepmc   +1 more source

Bowel Obstruction/Ileus Associated With the Use of Glucagon‐Like Peptide‐1 Receptor Agonists: A Nationwide Database Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9941-9954, November 2026.
ABSTRACT Aims The association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and the development of bowel obstruction/ileus remains unclear, and evidence for specific bowel obstruction/ileus subtypes remains limited. We examined the association between GLP‐1RA use and the incidence of bowel obstruction/ileus subtypes across different ...
Yuichiro Matsuo, Akira Okada, Takashi Sakamoto, Hideo Yasunaga   +3 more
wiley   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Design, Synthesis, and Biological Evaluation of N-Acyl Pregnane Alkaloid Ester Derivatives as Acetylcholinesterase and α-Glucosidase Inhibitors. [PDF]

Chem Biodivers
Li W, Chen Y, Lu M, Zou J, Yu X, He K.
europepmc   +1 more source

Optimizing Fertilization in Double‐Rice Systems: Balancing Grain Yield, Soil Organic Carbon and Greenhouse Gas Emissions

Journal of Agronomy and Crop Science, Volume 212, Issue 6, November 2026.
Schematic diagram of yield enhancement, soil carbon sequestration and greenhouse gas mitigation under optimized fertilization regimes in double‐rice systems in the middle and lower reaches of the Yangtze River. ABSTRACT Addressing the urgent need to balance high yields with environmental sustainability in the Yangtze River's double‐rice systems, this ...
Chaoming Ma, Shiyu Qin, Hongen Liu, Wenjian Xia, Fengshuo Zhao, Zhaojun Nie, Haiyang Liu, Peng Zhao, Qian Zhang, Yongfei Ma, Long Wang, Guangxin Li, Mengchan Xie, Yifan Feng, Ningning Jin   +14 more
wiley   +1 more source

Ethnopharmacological insights into type 2 diabetes management by traditional Moroccan herbal teas: HPLC-MS characterization of phenolic compounds and their related antioxidant and enzyme inhibitory activities. [PDF]

BMC Complement Med Ther
Zayed A, El Jemli M, Kharbach M, Faouzi MEA, Radwan RA, Ezzat SM.   +5 more
europepmc   +1 more source

Design, Synthesis, In Vitro, and In Silico Enzymatic Evaluations of New Chrysin Sulfonohydrazide Derivatives as Potent α‑Glucosidase Inhibitors. [PDF]

ACS Omega
Ayandokun TF, Le DTK, Chavasiri W.
europepmc   +1 more source

Synthesis and glycosidase inhibiton of two types of <i>N</i>-alkylated 1-deoxynojirimycin derivatives. [PDF]

RSC Adv
Wang L, Zhao Y, Zeng L, Liu Z, Wang W, Bai X, Guo L.   +6 more
europepmc   +1 more source

Dual antidiabetic potential of arjunglucoside I and arjunetin from <i>Terminalia chebula</i> via modulation of insulin- and gluconeogenesis-related responses. [PDF]

Anim Cells Syst (Seoul)
Song YS, Huo C, Blöchle A, Parajuli N, Kim KH, Lee HJ.   +5 more
europepmc   +1 more source

Novel 4-formyl-1,3-phenylene-bisoxy-bis(methylene)-bis(1,2,3-triazole-<i>N</i>-phenylacetamide) derivatives as a new category of excellent α-glucosidase inhibitors. [PDF]

RSC Adv
Bakhshi Varzaneh S, Sayahi MH, Halimi M, Ghafouri SN, Dastyafteh N, Mojtabavi S, Larijani B, Mohammadi-Khanaposhtani M, Mahdavi M.   +8 more
europepmc   +1 more source