Results 261 to 270 of about 40,475 (311)
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Pyrimidinylmethylphenyl glucoside as novel C-aryl glucoside SGLT2 inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Novel C-aryl glucoside SGLT2 inhibitors containing pyrimidine motif were designed and synthesized for biological evaluation. Among the compounds assayed, pyrimidine containing methylthio moiety 11 g demonstrated the best in vitro inhibitory activity against SGLT2 in this series to date (IC(50)=10.7 nM).
Junwon, Lee +5 more
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Pharmacology & Therapeutics, 1990
A number of studies have shown that drug glucosidation occurs in vertebrates. This review summarizes information on the chemical, physical and biological properties of eleven drug glucosides. Three out of two hundred individuals exhibited a complete lack of amobarbital-N-glucoside formation. The data from a pair of identical twins who were deficient in
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A number of studies have shown that drug glucosidation occurs in vertebrates. This review summarizes information on the chemical, physical and biological properties of eleven drug glucosides. Three out of two hundred individuals exhibited a complete lack of amobarbital-N-glucoside formation. The data from a pair of identical twins who were deficient in
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Microbial glucosidation of dihydroxyanthraquinones. General properties of the glucosidation system
Folia Microbiologica, 1974Corresponding mono-β-d-glucosides were obtained by fermentation ofStreptomyces aureofaciens B 96 with four isomeric dihydroxyanthraquinones (alizarin, quinizarin, chrysazin and anthraflavin). The effect of some factors (sugar source, concentration of substrates, pH) on biosynthesis of 1-hydroxy-2-(β-d-glucopyranosyloxy)anthraquinone was studied and ...
J, Matĕjů +4 more
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Glucosides from Curculigo orchioides
Phytochemistry, 2005From the rhizomes of Curculigo orchioides two phenolic glucosides named orchiosides A and B were isolated besides four known compounds and their structures were elucidated by the combination of 2D-NMR analysis, mass spectrometry and chemical evidences.
Moumita, Gupta +2 more
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Stereoselective synthesis of 1,1-dialkyl-1-methoxymethyl glucosides (acetal-glucosides)
Carbohydrate Research, 1989The synthesis is described of highly acid-sensitive, 1,1-dialkyl-1-methoxymethyl glucosides (acetal-glucosides) as potential anti-cancer prodrugs. Reaction of 2,3,4,6-tetra-O-acetyl-1-O-trimethylsilyl-beta-D-glucopyranose (4) severally with various aliphatic and alicyclic ketones and methyl trimethylsilyl ether, in the presence of catalytic amounts of ...
L F, Tietze +3 more
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Acetophenone C-glucosides and stilbene O-glucosides in Upuna borneensis
Phytochemistry, 2004Three acetophenone C-glycosides; 2,4,6-trihydroxyacetophenone 3-C-beta-(2'-O-p-hydroxybenzoyl)-glucopyranoside, 2,4,6-trihydroxyacetophenone 3-C-beta-(2'-O-E-coumaroyl)-glucopyranoside, 2,4,6-trihydroxyacetophenone 3-C-beta-(2'-O-E-cinnamoyl)-glucopyranoside, and two resveratrol O-glycosides; piceid 2'-O-p-hydroxybenzoate and, piceid 2'-O-E-ferulate ...
Zulfiqar, Ali +6 more
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Cycloartane glucosides from juncus effusus
Phytochemistry, 1994Five new cycloartane glucosides, juncosides I-V, have been isolated from Juncus effusus. The structures have been determined on the basis of chemical and spectroscopic studies.
Corsaro M. M +4 more
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Fresenius' Zeitschrift für analytische Chemie, 1956
K. Söllner, H. Pluskal, H. Kurtenacker
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K. Söllner, H. Pluskal, H. Kurtenacker
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Glucoside XI.. Über die Glucoside des Glycerins
Helvetica Chimica Acta, 1922P. Karrer, O. Hurwitz
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