Expression of a Drosophila glutathione transferase in Arabidopsis confers ability to detoxify the environmental pollutant, and explosive, 2,4,6-trinitrotoluene [PDF]
The explosive 2,4,6-trinitrotoluene (TNT) is a significant, global environmental pollutant that is both toxic and recalcitrant to degradation. Given the sheer scale and inaccessible nature of contaminated areas, phytoremediation may be a viable clean-up ...
Bruce, Neil Charles +6 more
core +1 more source
Metabolic Reprogramming Analysis of Wheat Response to Low Temperature Stress Under Nitrogen Supply
Low temperature stress triggers a defense network that maintains growth at the expense of inhibiting photosynthesis and chlorophyll synthesis. Temperature recovery effectively repairs low temperature‐induced damage and enhances stress resistance, while nitrogen supply can further augment these protective processes to strengthen cold tolerance ...
Qiujuan Jiao +9 more
wiley +1 more source
2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot +33 more
wiley +1 more source
Flashy flagella: flagellin modification is relatively common and highly versatile among the Enterobacteriaceae [PDF]
Schematic diagrams of inserts within the fliDCAZ loci of FGI−/FMI− Enterobacteriaceae. Flanking genes are indicated by yellow arrows, predicted phage genes by blue arrows, fimbrial biogenesis genes by grey arrows and sugar/amino acid transporter genes by
Don A. Cowan, Pieter De Maayer
core +3 more sources
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska +6 more
wiley +1 more source
Identification of Potential Glucosyltransferase Inhibitors from Cinnamic Acid Derivatives Using Molecular Docking Analysis: A Bioinformatics Study [PDF]
Amir Taherkhani +5 more
openalex +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Congenital disorders of glycosylation: an update on defects affecting the biosynthesis of dolichol-linked oligosaccharides [PDF]
Defects in the biosynthesis of the oligosaccharide precursor for N-glycosylation lead to decreased occupancy of glycosylation sites and thereby to diseases known as congenital disorders of glycosylation (CDG).
Haeuptle, M A, Hennet, T
core +1 more source
AGP and EXO‐LIKE genes promote brassinosteroid‐dependent anisotropic growth
Summary The brassinosteroid pathway promotes anisotropic cell expansion; however, the effectors in this process remain unclear. Candidates include ARABINOGALACTAN PROTEIN (AGP) genes, which are prominent brassinosteroid‐responsive transcriptional targets, and EXORDIUM (EXO)‐LIKE (EXL) genes.
Daria Novikova +8 more
wiley +1 more source

