UDP-glucosyltransferase OsUGT75A promotes submergence tolerance during rice seed germination [PDF]
Nature Communications, 2023 Submergence stress represents a major obstacle limiting the application of direct seeding in rice cultivation. Under flooding conditions, coleoptile elongation can function as an escape strategy that contributes to submergence tolerance during seed ...
Yongqi He +8 more
doaj +4 more sources
UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice [PDF]
Nature Communications, 2020 Increasing grain yield needs to be put in the context of environmental stress. Here, the authors reveal that a UDP-glucosyltransferase is associated with regulation of rice grain size, abiotic stress tolerance, flavonoid-mediated auxin signaling, and ...
Nai-Qian Dong +16 more
doaj +2 more sources
Role of UDP-glucose ceramide glucosyltransferase in venous malformation
Frontiers in Cell and Developmental Biology, 2023 Venous malformation (VM) results from the abnormal growth of the vasculature; however, the detailed molecular mechanism remains unclear. As a glycosyltransferase, UDP-glucose ceramide glucosyltransferase (UGCG) is localized to the Golgi body and is a key
Liangliang Kong
exaly +3 more sources
Identification and Functional Characterisation of Two Oat UDP-Glucosyltransferases Involved in Deoxynivalenol Detoxification [PDF]
Toxins, 2022 Oat is susceptible to several Fusarium species that cause contamination with different trichothecene mycotoxins. The molecular mechanisms behind Fusarium resistance in oat have yet to be elucidated.
Alfia Khairullina +6 more
doaj +4 more sources
A Ubiquitously Expressed UDP-Glucosyltransferase, UGT74J1, Controls Basal Salicylic Acid Levels in Rice [PDF]
Plants, 2021 Salicylic acid (SA) is a phytohormone that regulates a variety of physiological and developmental processes, including disease resistance. SA is a key signaling component in the immune response of many plant species.
Daisuke Tezuka +4 more
doaj +2 more sources
Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside [PDF]
Toxins, 2015 Glycosylation is an important plant defense mechanism and conjugates of Fusarium mycotoxins often co-occur with their parent compounds in cereal-based food and feed.
Herbert Michlmayr +8 more
doaj +2 more sources
Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]
Nature CommunicationsCollagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim +12 more
doaj +2 more sources
Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues
Nature Communications, 2021 The Clostridium difficile virulence factors TcdA and TcdB contain a glucosyltransferase domain (GTD), which has both glucohydrolase (GH) and glucosyltransferase (GT) activities. Here, the authors characterize the transition state features of the TcdA and
Ashleigh S. Paparella +5 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2020 UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding.
Diego A. Caraballo +5 more
doaj +1 more source
UDP-glucose, cereblon-dependent proinsulin degrader
Scientific Reports, 2022 Insulin secretion is regulated in multiple steps, and one of the main steps is in the endoplasmic reticulum (ER). Here, we show that UDP-glucose induces proinsulin ubiquitination by cereblon, and uridine binds and competes for proinsulin degradation and ...
Jaeyong Cho +6 more
doaj +1 more source