Results 21 to 30 of about 46,014 (199)

Purification and Characterization of a UDP-Glucosyltransferase Produced by Legionella pneumophila [PDF]

Infection and Immunity, 2003
ABSTRACT Legionella pneumophila is the agent of Legionnaires' disease. It invades and replicates within eukaryotic cells, including aquatic protozoans, mammalian macrophages, and epithelial cells. The molecular mechanisms of the Legionella interaction with target cells are not fully defined. In
Iouri, Belyi, Michel R, Popoff, Nicholas P, Cianciotto   +2 more
openaire   +2 more sources

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target [PDF]

, 2013
The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabolite in both prokaryotes and eukaryotes. In fungi, it is the precursor for the synthesis of chitin, an essential component of the fungal cell wall.
Hurtado-Guerrero, Ramon, Ibrahim, Adel F. M., van Aalten, D.M.F., van Aalten, Daan M. F., Ferguson, Michael A. J.; id_orcid, Urbaniak, Michael D., Jin, Cheng, Jin, Cheng Jun, Raimi, Olawale G., Urbaniak, Mick, Ferguson, Michael A. J., Du, Ting, Fang, Wenxia   +12 more
core   +5 more sources

Diversification of phenolic glucosides by two UDP-glucosyltransferases featuring complementary regioselectivity

Microbial Cell Factories, 2022
AbstractBackgroundGlucoside natural products have been showing great medicinal values and potentials. However, the production of glucosides by plant extraction, chemical synthesis, and traditional biotransformation is insufficient to meet the fast-growing pharmaceutical demands.
Fei Guo, Xingwang Zhang, Cai You, Chengjie Zhang, Fengwei Li, Nan Li, Yuwei Xia, Mingyu Liu, Zetian Qiu, Xianliang Zheng, Li Ma, Gang Zhang, Lianzhong Luo, Fei Cao, Yingang Feng, Guang-Rong Zhao, Wei Zhang, Shengying Li, Lei Du   +18 more
openaire   +3 more sources

In silicoCharacterization of UGT74G1Protein in Stevia rebaudianaBertoni Accession MS007 [PDF]

Journal of Tropical Life Science, 2021
Due to its low-calorie property, Stevia rebaudianais being promoted as an alterna-tive sweetener for diabetic and obese patients. The steady demand in the market for high-quality stevia extracts presents a challenge for the enhanced production of ste ...
Afiqah Ramatullah Khan, Nor Iswani Mokthar, Nor Iswani Mokthar, Afiqah Ramatullah Khan   +3 more
doaj   +1 more source

Ethanol triggers grape gene expression leading to anthocyanin accumulation during berry ripening [PDF]

, 2002
Recent studies have shown that low doses of ethanol stimulate the maturation of some fruits. The present work showed that spraying Cabernet Sauvignon grapes, with 5% ethanol at veraison enhances the anthocyanin accumulation.
Chervin, Christian, Ashraf El Kereamy, Nepveu, Françoise, Moutounet, Michel, Nepveu, F., Christian Chervin, Chervin, C., Jean-Marc Souquet, Michel Moutounet, Monje, Marie-Carmen, Ford, Christopher, Roustan, Jean-Paul, Christopher M Ford, Helene Mondies, Mondies, H., Souquet, J., Mondies, Hélène, Roustan, J., Jean-Paul Roustan, Ford, C., Ford, Christopher M, van Heeswijck, Robyn, El-Kereamy, Ashraf, Van Heeswijck, R., Françoise Nepveu, Robyn van Heeswijck, Marie-Carmen Monje, Monje, M., El-Kereamy, A., Souquet, Jean-Marc, Moutounet, M.   +30 more
core   +1 more source

O-Glycosylation of thrombospondin type 1 repeats : identification and characterisation of β1,3-glucosyltransferase [PDF]

, 2008
Rare types of protein glycosylation often occur in a domain-specific manner required for important biological functions (Okajima et al. 2008). O-linked fucosylation, where the fucose is linked directly to the hydroxyl groups of serine or threonine ...
Keusch, Krisztina
core   +1 more source

Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.

PLoS Biology, 2013
Hypothalamic neurons are main regulators of energy homeostasis. Neuronal function essentially depends on plasma membrane-located gangliosides. The present work demonstrates that hypothalamic integration of metabolic signals requires neuronal expression ...
Viola Nordström, Monja Willershäuser, Silke Herzer, Jan Rozman, Oliver von Bohlen Und Halbach, Oliver von Bohlen Und Halbach, Sascha Meldner, Ulrike Rothermel, Sylvia Kaden, Fabian C Roth, Clemens Waldeck, Norbert Gretz, Martin Hrabě de Angelis, Andreas Draguhn, Martin Klingenspor, Hermann-Josef Gröne, Richard Jennemann   +16 more
doaj   +1 more source

Detoxification of the Fusarium Mycotoxin Deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana [PDF]

Journal of Biological Chemistry, 2003
Plant pathogenic fungi of the genus Fusarium cause agriculturally important diseases of small grain cereals and maize. Trichothecenes are a class of mycotoxins produced by different Fusarium species that inhibit eukaryotic protein biosynthesis and presumably interfere with the expression of genes induced during the defense response of the plants.
Adam, Gerhard, Poppenberger-Sieberer, Brigitte, Berthiller, Franz, Lucyshyn, Doris, Sieberer, Tobias, Schuhmacher, Rainer, Krska, Rudolf, Kuchler, Karl, Glössl, Josef, Luschnig, Christian   +9 more
openaire   +3 more sources

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Characterization of a novel silkworm (Bombyx mori) phenol UDP‐glucosyltransferase [PDF]

European Journal of Biochemistry, 2002
Sugar conjugation is a major pathway for the inactivation and excretion of both endogenous and exogenous compounds. We report here the molecular cloning and functional characterization of a phenol UDP‐glucosyltransferase (UGT) from the silkworm, Bombyx mori, which was named BmUGT1. The complete cDNA clone is 1.6 kb, and the gene is expressed in several
Teresa, Luque, Kazuhiro, Okano, David R, O'Reilly   +2 more
openaire   +2 more sources