The UDP-glucosyltransferase multigene family in
BMC Genomics, 2008 Background Glucosidation plays a major role in the inactivation and excretion of a great variety of both endogenous and exogenous compounds. A class of UDP-glycosyltransferases (UGTs) is involved in this process.
Lu Cheng +6 more
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Highly efficient biosynthesis of salidroside by a UDP-glucosyltransferase-catalyzed cascade reaction
Biotechnology Letters, 2023 Objective Salidroside is an important plant-derived aromatic compound with diverse biological properties. The main objective of this study was to synthesize salidroside from tyrosol using UDP-glucosyltransferase (UGT) with in situ regeneration of UDP ...
Guosi Li, Liu Xinyang
exaly +4 more sources
Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]
Nature CommunicationsCollagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim +12 more
doaj +4 more sources
The expression of ecdysteroid UDP-glucosyltransferase enhances cocoon shell ratio by reducing ecdysteroid titre in last-instar larvae of silkworm, Bombyx mori. [PDF]
Sci Rep, 2018 Ecdysteroid UDP glucosyltransferase (EGT) is a baculovirus-encoded protein which can hinder the normal molting of insects by inactivating 20-hydroxyecdysone (20E).
Shen G +8 more
europepmc +2 more sources
Identification, Molecular Cloning, and Functional Characterization of a Wheat UDP-Glucosyltransferase Involved in Resistance to Fusarium Head Blight and to Mycotoxin Accumulation. [PDF]
Front Plant Sci, 2018 Plant uridine diphosphate (UDP)-glucosyltransferases (UGT) catalyze the glucosylation of xenobiotic, endogenous substrates and phytotoxic agents produced by pathogens such as mycotoxins.
Gatti M +6 more
europepmc +2 more sources
Identification and Functional Characterisation of Two Oat UDP-Glucosyltransferases Involved in Deoxynivalenol Detoxification [PDF]
Toxins, 2022 Oat is susceptible to several Fusarium species that cause contamination with different trichothecene mycotoxins. The molecular mechanisms behind Fusarium resistance in oat have yet to be elucidated.
Alfia Khairullina +6 more
doaj +4 more sources
Calcium/calmodulin alleviates substrate inhibition in a strawberry UDP-glucosyltransferase involved in fruit anthocyanin biosynthesis. [PDF]
BMC Plant Biol, 2016 UDP-glucosyltransferase (UGT) is a key enzyme for anthocyanin biosynthesis, which by catalyzing glycosylation of anthocyanidins increases their solubility and accumulation in plants.
Peng H +4 more
europepmc +2 more sources
UDP-glucosyltransferase HvUGT13248 Confers Type II Resistance to Fusarium graminearum in barley.
Plant Physiology, 2023 Fusarium head blight (FHB) of barley (Hordeum vulgare) causes yield losses and accumulation of trichothecene mycotoxins (e.g., deoxynivalenol (DON)) in grains.
Gerit Bethke +14 more
semanticscholar +3 more sources
Phenobarbital Induction of UDP-glucosyltransferase Activity in Drosophila melanogaster Meigen [PDF]
Journal of Entomological Science, 2000 The inducibility of UDP-glucosyltransferase activities towards the exogenous substrates 1-naphthol and 2-naphthol and the endogenous metabolite xanthurenic acid was demonstrated in Drosophila melanogaster Meigen larvae and adults using phenobarbital as an inducer.
M. Dolores Real +2 more
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Role of UDP-glucose ceramide glucosyltransferase in venous malformation [PDF]
Frontiers in Cell and Developmental Biology, 2023 Venous malformation (VM) results from the abnormal growth of the vasculature; however, the detailed molecular mechanism remains unclear. As a glycosyltransferase, UDP-glucose ceramide glucosyltransferase (UGCG) is localized to the Golgi body and is a key
Sheng Chen +5 more
doaj +3 more sources