The UDP-glucosyltransferase multigene family in
Background Glucosidation plays a major role in the inactivation and excretion of a great variety of both endogenous and exogenous compounds. A class of UDP-glycosyltransferases (UGTs) is involved in this process.
Lu Cheng +6 more
doaj +3 more sources
Phenobarbital Induction of UDP-glucosyltransferase Activity in Drosophila melanogaster Meigen
The inducibility of UDP-glucosyltransferase activities towards the exogenous substrates 1-naphthol and 2-naphthol and the endogenous metabolite xanthurenic acid was demonstrated in Drosophila melanogaster Meigen larvae and adults using phenobarbital as an inducer.
M. Dolores Real +2 more
openaire +2 more sources
Cloning and Characterization of a Bean Udp-Glucosyltransferase cDNA Expressed During Plant-Bacterial Interactions [PDF]
A cDNA clone, which corresponds to an RNA transcript that accumulates in bean during the hypersensitive reaction, was isolated and designated Hra25 (for hypersensitive reaction associated). Hra25 is predicted to encode a UDP-glucosyltransferase. Northern
T. A. Sullivan +2 more
doaj +3 more sources
UDP-glucosyltransferase PpUGT85A2 controls volatile glycosylation in peach. [PDF]
The monoterpene linalool is a major contributor to aroma and flavor in peach (Prunus persica) fruit. It accumulates during fruit ripening, where up to ~40% of the compound is present in a non-volatile glycosylated form, which affects flavor quality and consumer perception by retronasal perception during tasting.
Wu B +6 more
europepmc +3 more sources
Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target [PDF]
The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabolite in both prokaryotes and eukaryotes. In fungi, it is the precursor for the synthesis of chitin, an essential component of the fungal cell wall.
Hurtado-Guerrero, Ramon +12 more
core +5 more sources
UDP-glucosyltransferase activity of housefly microsomal fraction [PDF]
Housefly UDP-glucosyltransferase activity towards p-nitrophenol was demonstrated in a system in vitro. The activity is localized in the microsomal fraction, requires UDP-glucose, is slightly stimulated by Mg2+ and is activated optimally over a wide range of detergent concentration.
A, Morello, Y, Repetto
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Purification and kinetic analysis of a baculovirus ecdysteroid UDP-glucosyltransferase [PDF]
The baculovirus ecdysteroid UDP-glucosyltransferase (EGT) disrupts the hormonal balance of the insect host by catalysing the conjugation of ecdysteroids, the moulting hormones, with the sugar moiety from UDP-glucose or UDP-galactose. In this study, Autographa californica nucleopolyhedrovirus EGT has been overproduced and purified, and its kinetic ...
O P, Evans, D R, O'reilly
openaire +4 more sources
Highly Efficient Biosynthesis of Salidroside by a UDP-glucosyltransferase-catalyzed Cascade Reaction
Abstract Objective Salidroside is an important plant-derived aromatic compound with diverse biological properties. The main objective of this study was to synthesize salidroside from tyrosol using UDP-glucosyltransferase (UGT) with in situ regeneration of UDP-glucose (UDPG).
Guosi Li +7 more
openaire +2 more sources
AbstractBackgroundGlucoside natural products have been showing great medicinal values and potentials. However, the production of glucosides by plant extraction, chemical synthesis, and traditional biotransformation is insufficient to meet the fast-growing pharmaceutical demands.
Fei Guo +18 more
openaire +3 more sources
Purification and Characterization of a UDP-Glucosyltransferase Produced by Legionella pneumophila [PDF]
ABSTRACT Legionella pneumophila is the agent of Legionnaires' disease. It invades and replicates within eukaryotic cells, including aquatic protozoans, mammalian macrophages, and epithelial cells. The molecular mechanisms of the Legionella interaction with target cells are not fully defined. In
Iouri, Belyi +2 more
openaire +2 more sources

