Cloning and Characterization of a Bean Udp-Glucosyltransferase cDNA Expressed During Plant-Bacterial Interactions [PDF]
Molecular Plant-Microbe Interactions, 2001 A cDNA clone, which corresponds to an RNA transcript that accumulates in bean during the hypersensitive reaction, was isolated and designated Hra25 (for hypersensitive reaction associated). Hra25 is predicted to encode a UDP-glucosyltransferase. Northern
T. A. Sullivan +2 more
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UDP-glucosyltransferase PpUGT85A2 controls volatile glycosylation in peach. [PDF]
J Exp Bot, 2019 The monoterpene linalool is a major contributor to aroma and flavor in peach (Prunus persica) fruit. It accumulates during fruit ripening, where up to ~40% of the compound is present in a non-volatile glycosylated form, which affects flavor quality and consumer perception by retronasal perception during tasting.
Wu B +6 more
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Alternative transcript splicing regulates UDP-glucosyltransferase-catalyzed detoxification of DIMBOA in the fall armyworm (Spodoptera frugiperda). [PDF]
Sci Rep, 2022 Herbivorous insects often possess the ability to detoxify chemical defenses from their host plants. The fall armyworm (Spodoptera frugiperda), which feeds principally on maize, detoxifies the maize benzoxazinoid 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3 ...
Israni B +9 more
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UDP-glucosyltransferase activity of housefly microsomal fraction [PDF]
Biochemical Journal, 1979 Housefly UDP-glucosyltransferase activity towards p-nitrophenol was demonstrated in a system in vitro. The activity is localized in the microsomal fraction, requires UDP-glucose, is slightly stimulated by Mg2+ and is activated optimally over a wide range of detergent concentration.
A, Morello, Y, Repetto
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Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues
Nature Communications, 2021 The Clostridium difficile virulence factors TcdA and TcdB contain a glucosyltransferase domain (GTD), which has both glucohydrolase (GH) and glucosyltransferase (GT) activities. Here, the authors characterize the transition state features of the TcdA and
Ashleigh S. Paparella +5 more
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Purification and kinetic analysis of a baculovirus ecdysteroid UDP-glucosyltransferase [PDF]
Biochemical Journal, 1998 The baculovirus ecdysteroid UDP-glucosyltransferase (EGT) disrupts the hormonal balance of the insect host by catalysing the conjugation of ecdysteroids, the moulting hormones, with the sugar moiety from UDP-glucose or UDP-galactose. In this study, Autographa californica nucleopolyhedrovirus EGT has been overproduced and purified, and its kinetic ...
O P, Evans, D R, O'reilly
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Highly Efficient Biosynthesis of Salidroside by a UDP-glucosyltransferase-catalyzed Cascade Reaction
Biotechnology Letters, 2023 Abstract Objective Salidroside is an important plant-derived aromatic compound with diverse biological properties. The main objective of this study was to synthesize salidroside from tyrosol using UDP-glucosyltransferase (UGT) with in situ regeneration of UDP-glucose (UDPG).
Guosi Li +7 more
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Purification and Characterization of a UDP-Glucosyltransferase Produced by Legionella pneumophila [PDF]
Infection and Immunity, 2003 ABSTRACT Legionella pneumophila is the agent of Legionnaires' disease. It invades and replicates within eukaryotic cells, including aquatic protozoans, mammalian macrophages, and epithelial cells. The molecular mechanisms of the Legionella interaction with target cells are not fully defined. In
Iouri, Belyi +2 more
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G3: Genes, Genomes, Genetics, 2020 UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding.
Diego A. Caraballo +5 more
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UDP-glucose, cereblon-dependent proinsulin degrader
Scientific Reports, 2022 Insulin secretion is regulated in multiple steps, and one of the main steps is in the endoplasmic reticulum (ER). Here, we show that UDP-glucose induces proinsulin ubiquitination by cereblon, and uridine binds and competes for proinsulin degradation and ...
Jaeyong Cho +6 more
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