Results 71 to 80 of about 6,830 (220)

Understanding exosomes in regenerative dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad   +2 more
wiley   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

open access: yesAngewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster   +13 more
wiley   +2 more sources

Genome‐Wide Association Studies of Micro‐and Macro‐Mineral Concentrations in Cultivated, Wild and Native Pea

open access: yesLegume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Pea (Pisum sativum) is a nutrient‐rich crop that can provide essential nutrients needed for human and animal health. Improving its mineral concentration through genetic selection can enhance its nutritional value and help combat micronutrient deficiencies. This study aimed to investigate the genetic basis of the accumulation of eight minerals (
Maryam Bagheri   +4 more
wiley   +1 more source

Constitutive expression of UDP-glucosyltransferases from Haemonchus contortus [PDF]

open access: yes, 2018
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Lucie Nekovová Supervisor: Ing. Petra Matoušková, Ph.D.
Nekovová, Lucie
core  

Genetic control underlying dynamics of blueberry bioactive compounds during postharvest can drive breeding for functional fruits

open access: yesThe Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Blueberries (Vaccinium spp.) are widely recognized as a superfruit due to their high content health‐promoting bioactive compounds, including flavonoids and phenolic acids. While these metabolites provide significant health benefits, their postharvest stability and implications for shelf life are not well characterized, a fact that is essential
Estefania Tavares Flores   +8 more
wiley   +1 more source

Scanning Electron Microscopic study of Piper betle L. leaves extract effect against Streptococcus mutans ATCC 25175

open access: yesJournal of Applied Oral Science, 2011
INTRODUCTION: Previous studies have shown that Piper betle L. leaves extract inhibits the adherence of Streptococcus mutans to glass surface, suggesting its potential role in controlling dental plaque development. OBJECTIVES: In this study, the effect of
Zubaidah Haji Abdul Rahim   +1 more
doaj   +1 more source

Plant Glycosides and Glycosidases: A Treasure-Trove for Therapeutics

open access: yesFrontiers in Plant Science, 2020
Plants contain numerous glycoconjugates that are metabolized by specific glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing synthetic transglycosylation reactions.
Kassiani Kytidou   +4 more
doaj   +1 more source

SbWRKY62 Coordinates With SbERF096 to Activate Pterostilbene Biosynthesis and Targets a Xylanase Inhibitor Protein for Anthracnose Resistance in Sorghum

open access: yesPlant, Cell &Environment, Volume 49, Issue 12, Page 9524-9539, December 2026.
ABSTRACT Sorghum anthracnose caused by Colletotrichum sublineola (C. sublineola) is a destructive disease leading to severe crop damages. Pterostilbene is a phytoalexin that contributes to defence responses in sorghum, but the transcriptional regulation of its biosynthesis remained poorly understood.
Yajing Li   +5 more
wiley   +1 more source

Studies on the sucrose binding site of the glucosyltransferases of Leuconostoc and Streptococcus bacteria

open access: yes, 1985
para-Nitrophenyl-(alpha)-D-glucopyranoside was found to be a substrate for the glucosyltransferases produced by several species of Streptococcus and Leuconostoc bacteria.
Binder, Thomas
core   +1 more source

Streptococcus mutans biofilm inhibition using antisense oligonucleotide to glucosyltransferases B and C

open access: yesActa Medica Lituanica, 2015
Background. Biofilm formation by Streptococcus mutans bacteria on teeth leads to dental caries, which still remains one of the most prevalent human diseases strongly related to increase of dietary sucrose consumption in modern society.
Povilas Kalesinskas   +4 more
doaj   +1 more source

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