Results 41 to 50 of about 6,830 (220)

Recombinant expression and functional characterisation of regiospecific flavonoid glucosyltransferases from Hieracium pilosella L. [PDF]

open access: yes, 2009
Five glucosyltransferases were cloned by RT-PCR amplification using total RNA from Hieracium pilosella L. (Asteraceae) inflorescences as template. Expression was accomplished in Escherichia coli, and three of the HIS-tagged enzymes, UGT90A7, UGT95A1, and
Martens, S.   +4 more
core   +1 more source

Functions and regulation of cytokinin glucosyltransferases [PDF]

open access: yes
Cytokinins can be conjugated to N- and O-glucosides. While N-glucosylation generally leads to irretrievable loss of activity, O-glucosides are thought to play an important role in cytokinin storage and homeostasis since they can be hydrolyzed to the ...
Pineda Rodó, Albert
core   +2 more sources

Structure-based domain sequence alignments of DcUSAGT1 with UDP-glucose: glucosyltransferases in other plants.

open access: yes, 2016
Structure-based domain sequence alignments of DcUSAGT1 with UDP-glucose: glucosyltransferases in other plants.
Zhi-Sheng Xu (152820)   +2 more
core   +1 more source

Polyphenol-rich extract from propolis reduces the expression and activity of Streptococcus mutans glucosyltransferases at subinhibitory concentrations [PDF]

open access: yes, 2016
Publisher Copyright: © 2016 Jorge Jesús Veloz et al.Tooth decay is an infectious disease, whose main causative agent identified is Streptococcus mutans (S. mutans). Diverse treatments have been used to eradicate this microorganism, including propolis. To
Salazar, Luis A.   +5 more
core   +1 more source

Targeting cariogenic virulence of Streptococcus mutans by pinosylvin: a promising anti-cariogenic natural agent

open access: yesFrontiers in Microbiology
Dental caries continues to be a serious worldwide public health issue, with Streptococcus mutans (S. mutans) identified as the primary etiological pathogen. This study aimed to evaluate the anti-cariogenic potential of pinosylvin (PIN) against S. mutans.
Jingyan Shu   +12 more
doaj   +1 more source

Identification and Functional Characterisation of Two Oat UDP-Glucosyltransferases Involved in Deoxynivalenol Detoxification

open access: yesToxins, 2022
Oat is susceptible to several Fusarium species that cause contamination with different trichothecene mycotoxins. The molecular mechanisms behind Fusarium resistance in oat have yet to be elucidated.
Alfia Khairullina   +6 more
doaj   +1 more source

Transcriptome Analysis of the Barley–Deoxynivalenol Interaction: Evidence for a Role of Glutathione in Deoxynivalenol Detoxification

open access: yesMolecular Plant-Microbe Interactions, 2010
Trichothecenes are a major group of toxins produced by phytopathogenic fungi, including Fusarium graminearum. Trichothecenes inhibit protein synthesis in eukaryotic cells and are toxicologically relevant mycotoxins for humans and animals.
Stephanie A. Gardiner   +6 more
doaj   +1 more source

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

open access: yesAdvanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo   +10 more
wiley   +1 more source

O-glucosyltransferases in wheat (triticum aeshvum) and the competing weed black-grass (alopecurus myosuroides) [PDF]

open access: yes, 2003
The glucosylation of xenobiotics, catalysed by UDP-glucose dependent O-Glucosyltransferases (OGTs), is a major route of pesticide metabolism in wheat {Triticum aestivum L.).
Brazier, Melissa Catherine
core  

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane   +4 more
wiley   +1 more source

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