Results 41 to 50 of about 11,516 (271)

In vitro screening of probiotic lactic acid bacteria and prebiotic glucooligosaccharides to select effective synbiotics [PDF]

, 2010
Probiotics and prebiotics have been demonstrated to positively modulate the intestinal microflora and could promote host health. Although some studies have been performed on combinations of probiotics and prebiotics, constituting synbiotics, results on ...
Courtin, Céline, Durand, Henri, Grimoud, Julien, Monsan, Pierre, Ouarné, Françoise, Roques, Christine, Theodorou, Vassilia   +6 more
core   +2 more sources

Identification and Functional Characterisation of Two Oat UDP-Glucosyltransferases Involved in Deoxynivalenol Detoxification

Toxins, 2022
Oat is susceptible to several Fusarium species that cause contamination with different trichothecene mycotoxins. The molecular mechanisms behind Fusarium resistance in oat have yet to be elucidated.
Alfia Khairullina, Nikos Tsardakas Renhuldt, Gerlinde Wiesenberger, Johan Bentzer, David B. Collinge, Gerhard Adam, Leif Bülow   +6 more
doaj   +1 more source

Transcriptome Analysis of the Barley–Deoxynivalenol Interaction: Evidence for a Role of Glutathione in Deoxynivalenol Detoxification

Molecular Plant-Microbe Interactions, 2010
Trichothecenes are a major group of toxins produced by phytopathogenic fungi, including Fusarium graminearum. Trichothecenes inhibit protein synthesis in eukaryotic cells and are toxicologically relevant mycotoxins for humans and animals.
Stephanie A. Gardiner, Jayanand Boddu, Franz Berthiller, Christian Hametner, Robert M. Stupar, Gerhard Adam, Gary J. Muehlbauer   +6 more
doaj   +1 more source

Antibacterial and antibiofilm activities of Prangos acaulis Bornm. extract against Streptococcus mutans: an in silico and in vitro study [PDF]

, 2018
Introduction: Streptococcus mutans is a principal pathogenic agent in biofilm formation on the teeth surfaces and subsequently development of dental caries and plaque.
Behbahani, Mandana., Mohabatkar, Hassan., Nosrati, Mokhtar., Shakeran, Zahra.   +3 more
core   +2 more sources

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Natural CCD2 Variants and RNA Interference for Boosting Crocin Biosynthesis in Tomato

Biology
Crocin biosynthesis involves a complex network of enzymes with biosynthetic and modifier enzymes, and the manipulation of these pathways holds promise for improving human health through the broad exploitation of these bioactive metabolites.
Elena Moreno-Giménez, Eduardo Parreño, Lucía Morote, Alberto José López Jiménez, Cristian Martínez Fajardo, Silvia Presa, Ángela Rubio-Moraga, Antonio Granell, Oussama Ahrazem, Lourdes Gómez-Gómez   +9 more
doaj   +1 more source

Cloning, Expression, Purification, and Preliminary Characterization of Single-Crystal X-Ray Diffraction of Glucosyltransferase B of

Natural Product Communications, 2019
Dental caries characterized by acid damage of tooth enamel is a persistent disease that begins with the formation of biofilms on the tooth surface. The secreted glucosyltransferases enable Streptococcus mutans to synthesize extracellular glucan polymers ...
Joshua L. Mieher, Norbert Schormann, Manisha Patel, Hui Wu, Champion Deivanayagam   +4 more
doaj   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Synthesis of 3,5,3′, 4′-Tetrahydroxy--stilbene4′-O-β-D-glucopyranoside by Glucosyltransferases from

Natural Product Communications, 2013
Two glucosyltransferase isozymes from Phytolacca americana, PaGT3 and PaGT2 , catalyzed stereo- and regio-selective monoglucosylation of 3,5,3′,4′- tetrahydroxy-trans-stilbene to yield 3,5,3′,4′-tetrahydroxy-trans-stilbene-4′-O-β-D-glucopyranoside.
Tomoya Iwakiri, Hiroya Imai, Hiroki Hamada, Toru Nakayama, Shin-ichi Ozaki   +4 more
doaj   +1 more source

Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]

, 2019
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing, Tian, Li, Wilson, Alexander E, Wu, Sheng   +3 more
core   +1 more source