Results 11 to 20 of about 31,424 (230)
Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas
European Journal of Histochemistry, 2016 The proteoglycan syndecan-1 and the endoglucuronidases heparanase-1 and heparanase-2 are involved in molecular pathways that deregulate cell adhesion during carcinogenesis.
J. Waisberg +6 more
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Molecules, 2022 Currently the discovery and development of potent β-glucuronidase inhibitors is an active area of research due to the observation that increased activity of this enzyme is associated with many pathological conditions, such as colon cancer, renal diseases,
Sarosh Iqbal +7 more
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Annals of Human Biology, 2018 Background: Genetic variation in glucuronosyltransferases (UGT) is crucial in drug metabolism and risk of some diseases. Aim: To examine genetic variation in UGT in North African populations.
Apolonia Novillo +7 more
doaj +1 more source
Genetics and Molecular Biology, 2006 Bacterial beta-glucuronidase activity in the gut increases the enterohepatic circulation of toxic compounds and plays a major role in the etiology of colon cancer.
Diane Beaud +4 more
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Molecules, 2019 β-glucuronidase is a lysosomal glycosidase enzyme which catalyzes the extracellular matrix of cancer and normal cells and the glycosaminoglycans of the cell membrane, which is important for cancer cell proliferation, invasion, and metastasis.
El Hassane Anouar +9 more
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Scientific Reports, 2023 PCOS is a prevalent endocrine disorder among women of reproductive age, characterized by hormonal imbalances and metabolic disturbances. This study explores the correlation between gut microbial β-glucuronidase and β-glucosidase and PCOS, focusing on ...
Jalpa Patel +4 more
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Pharmaceuticals, 2023 Analyzing urine is common in drug-facilitated sexual assault cases if the analysis of blood is not optimal. The efficient enzymatic pretreatment of urine is important for cleaving glucuronides and improving the detection of the parent drug.
Kathrine Skov +4 more
doaj +1 more source
Indonesian Journal of Biotechnology, 2013 This study was carried out to establish a stable genetic transformation in callus culture of Andrographispaniculata mediated by Agrobacterium tumefaciens. The leaf disks of A. paniculata were infected with A.
Erly Marwani +2 more
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Acta Veterinaria, 2016 The effect of the probiotic strain Lactobacillus plantarum LS/07 on intestinal bacterial enzyme activities – β-glucuronidase (β-GLUCUR), β-galactosidase (β-GAL), and β-glucosidase (β-GLU) in the prevention of cancer, atherosclerosis and dysbiosis was ...
Hijová Emília +9 more
doaj +1 more source
Tethered Indoxyl-Glucuronides for Enzymatically Triggered Cross-Linking
Molecules, 2023 Indoxyl-glucuronides, upon treatment with β-glucuronidase under physiological conditions, are well known to afford the corresponding indigoid dye via oxidative dimerization.
Juno Son +6 more
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