Results 101 to 110 of about 12,956 (251)

Cortisol Stability at 16 and 30 Years in Urine Specimens Stored at −20°C

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Objective This study aims to investigate whether urinary cortisol can be reliably measured after long‐term storage at −20°C, using urine samples collected in 1993 from rural Bangladeshi women, and assayed after 16 and 30 years (2009 and 2023). Methods Specimens were collected by participants, placed in coolers with ice packs, transported to a ...
Anwesha Pan, Madison Saunders, Darryl J. Holman   +2 more
wiley   +1 more source

Accelerated Extraction and Analysis of Ethyl Glucuronide in Hair by Means of Pressurized Liquid Extraction Followed by Liquid Chromatography–Tandem Mass Spectrometry Determination

, 2020
Flaminia Vincenti, Camilla Montesano, Eleonora Oliva, Federico Fanti, Marco Vincenti, Alberto Salomone, Darío Compagnone, Roberta Curini, Manuel Sergi   +8 more
openalex   +2 more sources

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 953-963, April 2026.
Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo, Outi Lapatto‐Reiniluoto, Mika Kurkela, Mikko Neuvonen, Eeva Moilanen, Mikko Niemi, Aleksi Tornio, Janne T. Backman   +7 more
wiley   +1 more source

Reverse-phase HPLC purification for an extremely unstable glucuronide metabolite

, 2020
Dawn Sun, Dauh‐Rurng Wu, Peng Li, Henry Yip, Arvind Mathur   +4 more
openalex   +1 more source

Supplementary Table S2 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b

, 2023
Aksana Vasilyeva, Selvi Durmuş, Lie Li, Els Wagenaar, Shuiying Hu, Alice A. Gibson, John C. Panetta, Sridhar Mani, Alex Sparreboom, Sharyn D. Baker, Alfred H. Schinkel   +10 more
openalex   +1 more source

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1095-1104, April 2026.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo, Donna A. Volpe, Anik Chaturbedi, Aanchal Shah, Ashok Krishna, Paula L Hyland, Giri Vegesna, Cheng‐Hui Hsiao, Ryan De Palma, Melanie Fein, Rodney Rouse, Jeffry Florian   +11 more
wiley   +1 more source

Glucuronide and Sulphate Conjugation in vivo and in vitro [PDF]

, 1959
Kelly Harper, G Calcutt
openalex   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin

Drug Testing and Analysis, Volume 18, Issue 4, Page 483-489, April 2026.
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand, Oliver Zierau, Detlef Thieme, Annekathrin Martina Keiler   +3 more
wiley   +1 more source

Ethyl Glucuronide in Hair: A 10‐Year Overview

Drug Testing and Analysis, Volume 18, Issue 4, Page 518-529, April 2026.
The present study builds on a unique collection of more than 68,000 hair EtG results collected in the Northen Italy between 2013 and 2022. We investigated trends in alcohol consumption in terms of age, gender, recidivism, applicants, sampling region, sampling length, across seasons, and the COVID‐19.
Sara Casati, Alessandro Ravelli, Roberta F. Bergamaschi, Caterina Fabbri, Erika Palmisano, Andrea Ostinelli, Gabriella Roda, Giuseppe Facchi, Marica Orioli   +8 more
wiley   +1 more source