Results 111 to 120 of about 24,745 (276)
Demonstration of two functionally heterogenous groups within the activities of UDP-glucuronosyltransferase towards a series of 4-alkyl-substituted phenols [PDF]
G. J. Wishart, Mary T. Campbell
openalex +1 more source
Given the global burden of CVDs as a leading cause of mortality, our review aims to address the urgent need for improved dietary interventions. Key findings highlight that blueberry anthocyanins enhance endothelial function, modulate inflammatory pathways, and mitigate oxidative stress.
Muhammad Tayyab Arshad+3 more
wiley +1 more source
Precocious development of uridine diphosphate glucuronosyltransferase activity during organ culture of foetal rat liver in the presence of glucocorticoids [PDF]
G. J. Wishart+3 more
openalex +1 more source
The positive influence of berberine on the nervous system can be attributed to its diverse effects on multiple targets. The effects of berberine include its antioxidant, anti‐apoptotic, anti‐necroptotic, and anti‐inflammatory properties, as well as its ability to induce autophagy.
Xiaolan Wang+5 more
wiley +1 more source
Dietary moderately oxidized oil activates the Nrf2 signaling pathway in the liver of pigs
Background Previous studies have shown that administration of oxidized oils increases gene expression and activities of various enzymes involved in xenobiotic metabolism and stress response in the liver of rats and guinea pigs.
Varady Juliane+4 more
doaj +1 more source
The effects of zinc sulfate on ethyl glucuronide immunoassay urine testing [PDF]
Published research in the Journal of Analytical Toxicology and the American Society for Clinical Pathology has confirmed that the presence of Zinc Sulfate in adulterated urine samples can influence the testing results using EMIT and ELISA immunoassay ...
Cawley, Shanna Marie
core +1 more source
Curcumin regulates several signaling pathways linked to neuroprotection, such as those that reduce oxidative stress, prevent Aβ formation, and decrease neuroinflammation. ABSTRACT Progressive neuronal loss and dysfunction characterize neurodegenerative diseases (NDs) such as Alzheimer's, Parkinson's, and Huntington's diseases, spinal cord injury, and ...
Md. Rezaul Islam+11 more
wiley +1 more source
Structure-activity relationships of nitrosamines and nitramines which stimulate UDP-glucuronosyltransferase activities in vitro [PDF]
Michio Matsui+3 more
openalex +1 more source
ABSTRACT Bocidelpar is a peroxisome proliferator‐activated receptor δ modulator designed to address mitochondrial impairment. Two open‐label, single‐dose phase 1 studies (NCT05117294/NCT04942964) investigated the effect of severe renal or mild/moderate hepatic impairment on bocidelpar pharmacokinetics and safety.
Megumi Iwai+10 more
wiley +1 more source
Clinical and molecular study of Egyptian pediatric patients with Crigler-Najjar syndrome
Background Crigler-Najjar syndrome (CNS) is a rare autosomal recessive inherited disorder caused by uridine diphosphate-glucuronosyltransferase (UGT) enzyme deficiency. The enzyme is encoded by the uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1)
Mohammed A. Khedr+6 more
doaj +1 more source