Results 111 to 120 of about 25,858 (256)

Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes [PDF]

, 2012
Hye Young Ji, Hyeri Lee, Sae Rom Lim, Jeong‐Han Kim, Hye Suk Lee   +4 more
openalex   +1 more source

Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat

CPT: Pharmacometrics & Systems Pharmacology
Vericiguat (Verquvo; US: Merck, other countries: Bayer) is a novel drug for the treatment of chronic heart failure. Preclinical studies have demonstrated that the primary route of metabolism for vericiguat is glucuronidation, mainly catalyzed by uridine ...
Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A. Jungmann, Corina Becker, Maximilian Lobmeyer, Maria E. Trujillo, Shiyao Xu, Rolf Burghaus, Michaela Meyer   +10 more
doaj   +1 more source

The Survival and Physiological Response of Calliptamus abbreviatus Ikonn (Orthoptera: Acrididae) to Flavonoids Rutin and Quercetin

Insects
Insect-resistant substances from plants are important natural resources that human beings can potentially develop and use to control pests. In this study, we explored the adverse effects of rutin and quercetin on grasshopper (Calliptamus abbreviatus), as
Xunbing Huang, Li Zheng, Yueyue Wang
doaj   +1 more source

UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes [PDF]

, 2015
Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu, Zhongqiu Liu   +9 more
openalex   +1 more source

La farmacogenetica dei farmaci antitumorali [PDF]

, 2014
La variabilità individuale nella risposta ai farmaci è molto importante in quanto può condizionare la riuscita di un trattamento farmacologico ed è dovuta, in gran parte, al profilo genetico.
IOFRIDA, CATERINA
core  

A hypothesis on the equilibrium between dopamine toxicity and detoxification: The roles of NQO2 and UDP-glucuronosyltransferases

, 2023
Jean A. Boutin, Gilles Ferry, Karine Reybier   +2 more
openalex   +1 more source

Differential Regulation of Two Uridine Diphospho-Glucuronosyltransferases, UGT2B15 and UGT2B17, in Human Prostate LNCaP Cells [PDF]

, 1997
Chantal Guillemette
openalex   +1 more source

Separation and purification of uridine diphosphate-glucuronosyltransferases by chromatofocusing on a high-performance liquid chromatograph.

, 1989
Hironori Takanashi, Hiroshi Homma, Michio Matsui   +2 more
openalex   +2 more sources

Relationship of circulating total bilirubin, UDP-glucuronosyltransferases 1A1 and the development of non-alcoholic fatty liver disease: a cross-sectional study [PDF]

, 2022
Xuefeng Ma, Zheng Xu, Shousheng Liu, Likun Zhuang, Mengke Wang, Yifen Wang, Yongning Xin, Shiying Xuan   +7 more
openalex   +1 more source

Changes in expressions of UDP-glucuronosyltransferases in placenta and fetal liver of rats before birth induced by maternal exposure to bisphenol A during pregnancy

环境与职业医学
BackgroundMaternal exposure to bisphenol A (BPA) during pregnancy is closely related to adverse growth and development conditions such as preterm birth and low birth weight, but the relevant mechanisms are still unclear.
Peili WANG, Jun WANG, Yichen ZHAO, Panjie WANG, Mingyue MA, Zhiwen DUAN, Xiucong PEI, Haiyang YU   +7 more
doaj   +1 more source