Results 171 to 180 of about 22,737 (234)

TATA-box polymorphism in the urine diphosphate glucuronosyl transferase gene in Portuguese patients with clinical diagnosis of gilbert syndrome [PDF]

, 2002
Barbot, José, Costa, Elísio, Santos, Rosário, Santos-Silva, Ermelinda, Vieira, Emília   +4 more
core  

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P-Glycoprotein Inhibition. [PDF]

Clin Pharmacol Drug Dev
Jia H, Ballard TE, Zhang L, Cohen L, Bergagnini-Kolev MC, Templeton IE, Jones HM, Yin W.   +7 more
europepmc   +1 more source

Flunitrazepam increases the risk of lamotrigine-induced cutaneous adverse reactions: Combined analysis of medical big data and clinical research. [PDF]

Psychiatry Clin Neurosci
Bando H, Goda M, Nakataki M, Hirai K, Nitta Y, Kawada K, Yoshioka T, Kanda M, Ogawa A, Mukuta-Murakami C, Tsujinaka K, Miyata K, Kitagawa K, Niimura T, Aizawa F, Yagi K, Izawa-Ishizawa Y, Chuma M, Naito T, Tasaki Y, Numata S, Ishizawa K.   +21 more
europepmc   +1 more source

Phase II study of FOLFIRI with low-dose irinotecan plus ramucirumab as second-line treatment in Japanese patients with metastatic colorectal cancer (study rindo). [PDF]

Jpn J Clin Oncol
Hattori N, Nakayama G, Umeda S, Kishida T, Takeda S, Ezaka K, Tsutsuyama M, Sakai M, Hattori M, Ito T, Kanda M, Tanaka C, Murotani K, Ando M, Kodera Y.   +14 more
europepmc   +1 more source

Hepatic UGT2B-Mediated Testosterone Clearance Promotes Lipid Accumulation in High-Fat-Diet-Induced MASLD. [PDF]

Nutrients
Zhou L, Zheng Y, Qiao Y, Xu X, Zhang D, Shi Y, Huang Y, Zeng H, Zeng T, Li X, Zhang L.   +10 more
europepmc   +1 more source

Genetic variation features of neonatal hyperbilirubinemia caused by inherited diseases.

World J Clin Pediatr
You JY, Xiong LY, Wu MF, Fan JS, Fu QH, Qiu MH.   +5 more
europepmc   +1 more source

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UDP-Glucuronosyltransferases

Current Drug Metabolism, 2000
Glucuronidation represents a major pathway which enhances the elimination of many lipophilic xenobiotics and endobiotics to more water-soluble compounds. The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen ...
C D, King, G R, Rios, M D, Green, T R, Tephly   +3 more
openaire   +2 more sources

Steroid UDP glucuronosyltransferases

The Journal of Steroid Biochemistry and Molecular Biology, 1992
The glucuronidation of steroids is a major process necessary for their elimination in the bile and urine. In general, steroid glucuronides are biologically less reactive than their parent steroids. However, in some cases often associated with disease and steroid therapy, more reactive or toxic glucuronides may be formed.
P I, Mackenzie, L, Rodbourne, S, Stranks
openaire   +2 more sources

Human UDP-Glucuronosyltransferase 2B7

Current Drug Metabolism, 2001
UDP-Glucuronosyltransferases (UGTs) are glycoproteins, localized in endoplasmic reticulum (ER) and nuclear membranes, which catalyze the confugation of a broad variety of lipophilic aglycon substrates with glucuronic acid using UDP-glucuronic acid (UDP-GlcUA) as the sugar donor.
A, Radominska-Pandya, J M, Little, P J, Czernik   +2 more
openaire   +2 more sources

UDP-Glucuronosyltransferases*

2010
United ...
Mackenzie, Peter Ian, Gardner-Stephen, Dione Anne, Miners, John Oliver   +2 more
openaire   +2 more sources