Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk +9 more
core +1 more source
Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats [PDF]
The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression in the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats.
Bell, Richard L. +8 more
core +1 more source
Transcriptome pathways unique to dehydration tolerant relatives of modern wheat [PDF]
Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock ...
AN Olsen +53 more
core +1 more source
Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis [PDF]
KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K.
CRISA A. +6 more
core
New Targets for an Old Drug: A Chemical Proteomics Approach to Unraveling the Molecular Mechanism of Action of Methotrexate [PDF]
Christopher M. Hosfield +8 more
core +1 more source
Machine learning-driving optimization and spatial assembly of a cell-free system for high-yield liquiritigenin production. [PDF]
Liu F +7 more
europepmc +1 more source
Neuro-Transcriptomic Responses to Polypharmacological Agents in <i>Danio rerio</i>: Implications for Translational Drug Repurposing in Neurodevelopmental Disorders. [PDF]
Bartkowiak AD, Mooney MR.
europepmc +1 more source
Pyropheophytin a accompanies pheophytin a in darkened light grown cells of Euglena [PDF]
RĂ¼diger, W. +4 more
core
Ammonia reduces glutamine synthetase expression in astrocytes via activation of Hippo-YAP signaling pathways. [PDF]
Nasu Y +6 more
europepmc +1 more source
Transcriptional regulator NtrC modulates nitrogen assimilation, virulence, and the extracellular glutamine synthetase activity in Acinetobacter baumannii. [PDF]
Alahmar AJ +3 more
europepmc +1 more source

