Results 151 to 160 of about 585,844 (339)

Metabotropic glutamate receptors: physiology, pharmacology, and disease.

Annual Review of Pharmacology and Toxicology, 2010
C. Niswender, P. Conn
semanticscholar   +1 more source

Characterization of structural component of cell walls of alkalophilic strain of Bacillus sp. C-125. Preparation of poly(γ-l-glutamate) from cell wall component

, 1987
Rikizo Aono
openalex   +2 more sources

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

L-Glutamato: un aminoácido clave para las funciones sensoriales y metabólicas

Archivos Latinoamericanos de Nutrición
El ácido glutámico como tal o en su forma ionizada L-glutamato (GLU) es uno de los aminoácidos más abundantes en la naturaleza debido a que cumple funciones importantes a nivel celular y sistémico.
Sonia Luz Albarracín, Manuel E Baldeón, Elba Sangronis, Alexandra Cucufate Petruschina, Felix G. R Reyes   +4 more
doaj  

Expression of SOD1 G93A or wild‐type SOD1 in primary cultures of astrocytes down‐regulates the glutamate transporter GLT‐1: lack of involvement of oxidative stress [PDF]

, 2003
Massimo Tortarolo, Andrew J. Crossthwaite, Laura Conforti, Jeremy P.E. Spencer, Robert J. Williams, Caterina Bendotti, Marcus Rattray   +6 more
openalex   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

Proceedings of the National Academy of Sciences of the United States of America, 1991
V. Dawson, T. Dawson, E. London, D. Bredt, S. Snyder   +4 more
semanticscholar   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Mitochondrial Ca²⁺ Signaling at the Tripartite Synapse: A Unifying Framework for Glutamate Homeostasis, Metabolic Coupling, and Network Vulnerability. [PDF]

Biomolecules
Mancuso M, Mezzalira F, Vignoli B, Greotti E.   +3 more
europepmc   +1 more source

Reviewer #2 (Public Review): Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure

openalex   +1 more source