Results 141 to 150 of about 382,255 (259)

A Non‐Covalent [4Fe–4S]/[2Fe] Interface in HydF Guides [FeFe]‐Hydrogenase Maturation

Angewandte Chemie, EarlyView.
Bridged or not? 57Fe NRVS reveals a non‐covalent, electronically coupled interaction between the HydF [4Fe–4S] cluster and the [2Fe] precursor. Boltz‐2 structure predictions suggest that the cubane organizes lipoate‐dependent Hmet chemistry, positioning intermediates for assembly of the CH2–NH–CH2 bridge during H‐cluster biosynthesis.
Giorgio Caserta, Princess R. Cabotaje, Armel T. Waffo, Deepak Prajapat, Ilya Sergueev, Stefan Frielingsdorf, Gustav Berggren   +6 more
wiley   +2 more sources

Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]

Oncol Res
Tralongo P, Ballato M, Zuccalà V, Fiorentino V, Giordano W, Casili G, Bellinghieri F, Caruso G, Angileri FF, Fadda G, Martini M, Caffo M.   +11 more
europepmc   +1 more source

Auf dem Weg zu chromoselektiven Transformationen in biologischen Systemen: Perspektiven und Herausforderungen

Angewandte Chemie, EarlyView.
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley   +1 more source

Generalized Analysis of Electrophilic Small Molecules

Angewandte Chemie, EarlyView.
Generalized fragmentation patterns stand to unlock the utility of tandem‐mass spectrometry for chemical reaction analysis but are bottlenecked by time consuming method development. Here were show how we can analyze most electrophilic small molecules the same way by their conjugation with a simple MS/MS encoded chemical probe.
Uma Neelakantan, Maowei Hu, Jiya Bhatia, Huyen N. Nguyen, John (Bobby) Yeboah, Eirinaios I. Vrettos, Dionysius Copoulos, Khue N. M. Nguyen, Madan M. Babu, Daniel J. Blair   +9 more
wiley   +2 more sources

Glutamate: Safe and Adequate Intake Levels for Infants-<i>Should Breast Milk Be Taken Off the Market?</i> [PDF]

Foods
Hartog A, Verhagen H.
europepmc   +1 more source

Structure and enzymology of glutaminase S482C and H461L variants associated with excess brain glutamate and neurological disease. [PDF]

J Biol Chem
Crane CS, McIssac TK, Milano SK, Cerione RA, Ulrich SM.   +4 more
europepmc   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Serum Glutamate in Dry Eye Disease: Associations with Symptoms and Clinical Signs. [PDF]

Diagnostics (Basel)
Desai B, Muralidhar R, Parchejo L, Chang J, Saccaro L, Aenlle K, Goldhardt R, Galor A.   +7 more
europepmc   +1 more source

Fabrication of Co-Doped Covalent Organic Framework Nanosheets with Mild Interlayer Stress for Quantitative Detection of Alzheimer's Disease Biomarkers. [PDF]

Biosensors (Basel)
Lv Y, Zhou Y, Liu Z, Dong H, Zheng H, Cheng S, Wang X, Lv C, Xu M.   +8 more
europepmc   +1 more source

Prefrontal Cortex Dysregulation of Amino Acid-Glucose Homeostasis Links High-Fat and/or High-Fructose Intake to Cognitive Deficits in Male Mice. [PDF]

Neurochem Res
Martínez-Orozco H, Reyes-Castro LA, Lomas-Soria C, Solís-Ortíz S, Diaz-Miranda SY.   +4 more
europepmc   +1 more source