Results 71 to 80 of about 227,873 (271)
Epilepsia, EarlyView.Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti +14 more
wiley +1 more source
The components required for amino acid neurotransmitter signaling are present in adipose tissues
Journal of Lipid Research, 2007 The adipocyte does not only serve as fuel storage but produces and secretes compounds with modulating effects on food intake and energy homeostasis.
Anne Nicolaysen +4 more
doaj +1 more source
The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review
Epilepsia, EarlyView.Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu +2 more
wiley +1 more source
Frontiers in MicrobiologyIntroductionLevilactobacillus brevis CRL 2013, a plant-derived lactic acid bacterium (LAB) with immunomodulatory properties, has emerged as an efficient producer of γ-aminobutyric acid (GABA).
Pablo G. Cataldo +6 more
doaj +1 more source
WONOEP XVII appraisal: The immunopathogenesis of epilepsy
Epilepsia, EarlyView.Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak +12 more
wiley +1 more source
International Journal of Molecular Sciences, 2013 We have developed a gamma-aminobutyric acid (GABA) production technique using his-tag mediated immobilization of Escherichia coli-derived glutamate decarboxylase (GAD), an enzyme that catalyzes the conversion of glutamate to GABA. The GAD was obtained at
Seungwoon Lee +5 more
semanticscholar +1 more source
The FEBS Journal, EarlyView.Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley +1 more source
Truncation of the Calmodulin Binding Domain in Rice Glutamate Decarboxylase 4 (OsGAD4) Leads to Accumulation of γ-Aminobutyric Acid and Confers Abiotic Stress Tolerance in Rice Seedlings [PDF]
, 2023 Nadia Akter +3 more
openalex +1 more source
Research in Molecular Medicine, 2015 Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA.
Abolghasem Esmaeili, Maliheh Dehghan
doaj
Establishment of a Stable Glutamate Decarboxylase (Gad) Expressing Cell-Line by Transfection
Cell Transplantation, 1993 We have constructed a recombinant DNA clone containing the gene encoding glutamic acid decarboxylase (GAD), which catalyzes the synthesis of γ-amino-butyric acid (GABA).
Feng C. Zhou +2 more
doaj +1 more source