Results 1 to 10 of about 2,775,779 (308)

CRF1/CRF2 and MC3/MC4 Receptors Affect Glutamate- Induced Food Intake in Neonatal Meat-Type Chicken

open access: yesBrazilian Journal of Poultry Science, 2019
Central glutamate, melanocortin and corticotropin systems have mediatory role on several physiologic functions in the brain, but their interactions on appetite regulation are not fully elicited.
F Ahmadi   +3 more
doaj   +1 more source

L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets. [PDF]

open access: yesPLoS ONE, 2014
L-Glutamate is a major oxidative fuel for the small intestine. However, few studies have demonstrated the effect of L-glutamate on the intestinal architecture and signaling of amino acids in the small intestine.
Meng Lin   +7 more
doaj   +1 more source

Mechanisms associated with activation of intracellular metabotropic glutamate receptor, mGluR5 [PDF]

open access: yes, 2016
The group 1 metabotropic glutamate receptor, mGluR5, is found on the cell surface as well as on intracellular membranes where it can mediate both overlapping and unique signaling effects.
Jong, Yuh-Jiin I, O\u27Malley, Karen L
core   +2 more sources

Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila

open access: yesBMC Biology, 2005
Background Drosophila discs-large (DLG) is the sole representative of a large class of mammalian MAGUKs, including human DLG, SAP 97, SAP102, and PSD-95. MAGUKs are thought to be critical for postsynaptic assembly at glutamatergic synapses.
Featherstone David E, Chen Kaiyun
doaj   +1 more source

A glutamate concentration‐biased allosteric modulator potentiates NMDA‐induced ion influx in neurons

open access: yesPharmacology Research & Perspectives, 2021
Precisely controlled synaptic glutamate concentration is essential for the normal function of the N‐methyl D‐aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that results in the ...
Blaise M. Costa   +8 more
doaj   +1 more source

Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]

open access: yes, 2014
Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean   +3 more
core   +2 more sources

Effect of glutamate antagonists on nitric oxide production in rat brain following intrahippocampal injection [PDF]

open access: yesArchives of Biological Sciences, 2007
Stimulation of glutamate receptors induces neuronal nitric oxide (NO) release, which in turn modulates glutamate transmission. The involvement of ionotropic glutamate NMDA and AMPA/kainate receptors in induction of NO production in the rat brain was ...
Radenović Lidija   +3 more
doaj   +1 more source

Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects [PDF]

open access: yes, 2015
The CRF system of the central nucleus of the amygdala (CeA) is important for the processing of anxiety, stress, and effects of acute and chronic ethanol.
CICCOCIOPPO, Roberto   +7 more
core   +1 more source

Glutamate Receptors in Plants [PDF]

open access: yesAnnals of Botany, 2002
Ionotropic glutamate receptors function in animals as glutamate-gated non-selective cation channels. Numerous glutamate receptor-like (GLR) genes have been identified in plant genomes, and plant GLRs are predicted, on the basis of sequence homology, to retain ligand-binding and ion channel activity. Non-selective cation channels are ubiquitous in plant
openaire   +3 more sources

Glutamate and its receptors in cancer [PDF]

open access: yesJournal of Neural Transmission, 2014
Glutamate, a nonessential amino acid, is a major bioenergetic substrate for proliferating normal and neoplastic cells on one hand and an excitatory neurotransmitter that is actively involved in biosynthetic, bioenergetic, metabolic, and oncogenic signaling pathways on the other.
Andrzej Stepulak   +3 more
openaire   +4 more sources

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