Glutamate receptor ion channels [PDF]
Current Opinion in Neurobiology, 2005 Glutamate receptor ion channels mediate excitatory responses at the majority of CNS synapses. They are the only ligand-gated ion channels for which multiple high-resolution crystal structures have been solved. Highlights of information gained from mechanistic studies based on the crystal structures of their ligand-binding domains include explanations ...
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What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit. [PDF]
, 2014 The GRIA1 locus, encoding the GluA1 (also known as GluRA or GluR1) AMPA glutamate receptor subunit, shows genome-wide association to schizophrenia. As well as extending the evidence that glutamatergic abnormalities have a key role in the disorder, this ...
Bannerman, D.M. +5 more
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The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor subunit composition [PDF]
, 2009 Pumilio (Pum) is a translational repressor that binds selectively to target mRNAs and recruits Nanos (Nos) as a corepressor. In the larval neuromuscular system, Pum represses expression of the translation factor eIF-4E and the glutamate receptor subunit ...
Andrews, Shane +4 more
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D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]
, 2005 Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D. +10 more
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Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]
, 2017 Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y +12 more
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Nitric oxide and synaptic function [PDF]
, 1994 The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
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What's a brain: neuroanatomy and neurochemistry of anxiety disorders in dogs [PDF]
, 2011 This review deals with the neurocircuitry of fear and anxiety disorders, with the focus on neuroanatomy and neurochemistry. This knowledge is required to correctly diagnose and treat dogs with anxiety-related behavioral disorders.
Audenaert, Kurt +6 more
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Large‐scale case‐control study of a functional polymorphism in the glutamate receptor, metabotropic 3 gene in patients with schizophrenia [PDF]
, 2008 Ayako Nunokawa +11 more
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Autoimmune Cerebellar Ataxia Associated with Anti-Glutamate Receptor δ2 Antibodies: a Rare but Treatable Entity [PDF]
, 2023 Laura Khatib +8 more
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