Results 1 to 10 of about 1,540,702 (294)

Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain

Journal of Biomedical Science, 2009
The antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the bark of Magnolia officinalis, were investigated on animal paw licking responses and thermal hyperalgesia induced by glutamate receptor agonists including ...
Ko Chien-Hsin, Lin Yu-Chin, Chen Hwei-Hsien, Lin Yi-Ruu, Chan Ming-Huan   +4 more
doaj   +1 more source

Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia

Mediators of Inflammation, 2013
Activation of the N-methyl-D-aspartate receptor (NMDAR) is fundamental in the development of hyperalgesia. Overactivation of this receptor releases superoxide and nitric oxide that, in turn, forms peroxynitrite (PN).
Carolina Muscoli, Concetta Dagostino, Sara Ilari, Filomena Lauro, Micaela Gliozzi, Erlisa Bardhi, Ernesto Palma, Vincenzo Mollace, Daniela Salvemini   +8 more
doaj   +1 more source

Long-Term Exposure to 6-PPD Quinone Inhibits Glutamate Synthesis and Glutamate Receptor Function Associated with Its Toxicity Induction in Caenorhabditis elegans

Toxics
6-PPD quinone (6-PPDQ) is widely distributed in environments. In Caenorhabditis elegans, we first examined the effects of 6-PPDQ on glutamate synthesis and receptor function by analyzing glutamate content, related gene expression, and phenotypes after ...
Wei Wang, Yunhui Li, Dayong Wang
doaj   +1 more source

Multiple serum anti-glutamate receptor antibody levels in clozapine-treated/naïve patients with treatment-resistant schizophrenia

BMC Psychiatry
Background Glutamatergic function abnormalities have been implicated in the etiology of treatment-resistant schizophrenia (TRS), and the efficacy of clozapine may be attributed to its impact on the glutamate system.
Jingqi He, Jinguang Li, Yisen Wei, Zhangyin He, Junyu Liu, Ning Yuan, Risheng Zhou, Xingtao He, Honghong Ren, Lin Gu, Yanhui Liao, Xiaogang Chen, Jinsong Tang   +12 more
doaj   +1 more source

Binge drinking triggers VGLUT3-mediated glutamate secretion and subsequent hepatic inflammation by activating mGluR5/NOX2 in Kupffer cells

Nature Communications
Glutamate, a crucial player in hepatic amino acid metabolism, has been relatively unexplored in immune cell activation. We show in a study with male mice that hepatic glutamate accumulates in vesicles of perivenous hepatocytes through vesicular glutamate
Keungmo Yang, Kyurae Kim, Tom Ryu, Young-Ri Shim, Hee-Hoon Kim, Sung Eun Choi, Min Jeong Kim, Katherine Po Sin Chung, Eunmi Lee, Kwang Woo Lee, Jehwi Jeon, Pilhan Kim, Young Seo Kim, Taeyun Ku, Haengdueng Jeong, Ki Taek Nam, Gyumin Lim, Dong Wook Choi, Seok-Hwan Kim, Hyuk Soo Eun, Won Kim, Won-Il Jeong   +21 more
doaj   +1 more source

Glutamate receptors and schizophrenia [PDF]

Journal of Psychopharmacology, 1987
B S, Meldrum, R W, Kerwin
openaire   +2 more sources

Configurational diversity of metabotropic glutamate receptor complexes with beta-arrestins. [PDF]

Nat Commun
Marx DC, Gonzalez-Hernandez AJ, Lee J, Siepe D, Weber WF, Huynh K, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Kalocsay M, Eliezer D, Levitz J.   +12 more
europepmc   +1 more source

Seizures in a cat with metabotropic glutamate receptor 1 (mGluR1) antibodies: a case report. [PDF]

Front Vet Sci
Putzer M, Hörmann A, Stegfellner V, Volk HA, Neßler JN.   +4 more
europepmc   +1 more source

Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins. [PDF]

Nat Commun
Marx DC, Huynh K, Gonzalez-Hernandez AJ, Strauss A, Rico C, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Eliezer D, Khelashvili G, Levitz J.   +11 more
europepmc   +1 more source

Case Report: Rare brainstem involvement in anti-metabotropic glutamate receptor 1 encephalitis. [PDF]

Front Immunol
Hu M, Zhou H, Yi X.
europepmc   +1 more source