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A Mathematical Model of Tripartite Synapse: Astrocyte Induced Synaptic Plasticity

open access: yes, 2012
In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a synaptic cleft and ...
Majumdar, Kaushik, Tewari, Shivendra
core   +1 more source

Neurotransmitter signaling in white matter [PDF]

open access: yes, 2014
Butt, Arthur M.   +2 more
core   +1 more source

Conformational diversity in class C GPCR positive allosteric modulation

open access: yesNature Communications
The metabotropic glutamate receptors (mGlus) are class C G protein-coupled receptors (GPCR) that form obligate dimers activated by the major excitatory neurotransmitter L-glutamate.
Giuseppe Cannone   +11 more
doaj   +1 more source

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