An unexpected role for a glutamate receptor. [PDF]
Science, 2023 γ-Aminobutyric acid acts on a glutamate receptor, evoking synaptic ...
Coombs ID, Farrant M.
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Regulation of dopamine D1 receptor dynamics within the postsynaptic density of hippocampal glutamate synapses. [PDF]
PLoS ONE, 2013 Dopamine receptor potently modulates glutamate signalling, synaptic plasticity and neuronal network adaptations in various pathophysiological processes. Although key intracellular signalling cascades have been identified, the cellular mechanism by which ...
Laurent Ladepeche +3 more
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Scientific Reports, 2022 Monosodium glutamate induces behaviors thought to reflect headache and nausea in rats. We explored the effects of the N-methyl-d-aspartate receptor antagonist (2R)-amino-5-phosphonovaleric acid, the inotropic glutamate receptor antagonist kynurenic acid,
Tarique Benbow +5 more
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Magnesium sulfate protects against the bioenergetic consequences of chronic glutamate receptor stimulation. [PDF]
PLoS ONE, 2013 Extracellular glutamate is elevated following brain ischemia or trauma and contributes to neuronal injury. We tested the hypothesis that magnesium sulfate (MgSO4, 3 mM) protects against metabolic failure caused by excitotoxic glutamate exposure.
Pascaline Clerc +5 more
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Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury. [PDF]
PLoS ONE, 2012 Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Despite
John C Gensel +3 more
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A Glio-Protective Role of mir-263a by Tuning Sensitivity to Glutamate
Cell Reports, 2017 Glutamate is a ubiquitous neurotransmitter, mediating information flow between neurons. Defects in the regulation of glutamatergic transmission can result in glutamate toxicity, which is associated with neurodegeneration.
Sherry Shiying Aw +3 more
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A glutamate concentration‐biased allosteric modulator potentiates NMDA‐induced ion influx in neurons
Pharmacology Research & Perspectives, 2021 Precisely controlled synaptic glutamate concentration is essential for the normal function of the N‐methyl D‐aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that results in the ...
Blaise M. Costa +8 more
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CRF1/CRF2 and MC3/MC4 Receptors Affect Glutamate- Induced Food Intake in Neonatal Meat-Type Chicken
Brazilian Journal of Poultry Science, 2019 Central glutamate, melanocortin and corticotropin systems have mediatory role on several physiologic functions in the brain, but their interactions on appetite regulation are not fully elicited.
F Ahmadi +3 more
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L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets. [PDF]
PLoS ONE, 2014 L-Glutamate is a major oxidative fuel for the small intestine. However, few studies have demonstrated the effect of L-glutamate on the intestinal architecture and signaling of amino acids in the small intestine.
Meng Lin +7 more
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BMC Biology, 2005 Background Drosophila discs-large (DLG) is the sole representative of a large class of mammalian MAGUKs, including human DLG, SAP 97, SAP102, and PSD-95. MAGUKs are thought to be critical for postsynaptic assembly at glutamatergic synapses.
Featherstone David E, Chen Kaiyun
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