Results 251 to 260 of about 396,749 (354)

Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740):  Identification of Two New Potent, Selective, and Systemically Active Agonists for Group II Metabotropic Glutamate Receptors

, 1999
James A. Monn, Matthew J. Valli, Steven M. Massey, Marvin M. Hansen, Thomas Kress, James P. Wepsiec, Allen R. Harkness, John L. Grutsch, Rebecca A. Wright, Bryan G. Johnson, Sherri L. Andis, Ann E. Kingston, Rosemarie Tomlinson, Richard A. Lewis, Kelly R. Griffey, Joseph P. Tizzano, Darryle D. Schoepp   +16 more
openalex   +1 more source

Distribution of glutamate receptor subtypes in the vertebrate retina

, 1995
Yuandong Peng, Craig Blackstone, Richard L. Huganir, King‐Wai Yau   +3 more
openalex   +1 more source

On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily

Angewandte Chemie International Edition, EarlyView.
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler, Torben F. Fürtges, Till Rudack, Reinhard Sterner   +3 more
wiley   +1 more source

Pharmacology, Signaling and Therapeutic Potential of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. [PDF]

ACS Pharmacol Transl Sci
Kos JA, Langiu M, Hellyer SD, Gregory KJ.   +3 more
europepmc   +1 more source

A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light

Anaëlle Dumazer, Roser Borràs‐Tudurí, Iona Truong, Xiaojing Cong, Fanny Malhaire, Xavier Rovira, Xavier Gómez‐Santacana, Laurent Givalois, Guillaume Lebon, Amadeu Llebaria, Cyril Goudet   +10 more
openalex   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

A type-5 metabotropic glutamate receptor-perineuronal net axis shapes the function of cortical GABAergic interneurons in chronic pain. [PDF]

J Anesth Analg Crit Care
Mascio G, Nicoletti F, Battaglia G, Notartomaso S.   +3 more
europepmc   +1 more source

A new specific neuronal modulatory effect of nicotine: the functional cross talk between nicotinic and glutamate receptors

, 2014
Mario Marchi, Anna Pittaluga, Massimo Grilli   +2 more
openalex   +1 more source

Modulating Taste Perception in Newly Weaned Piglets: The Role of Palatability Additives in Enhancing Feed Intake and Performance

Animal Research and One Health, EarlyView.
Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht, Gabriela Altenhofen, Daiane Carvalho, Michele Fangmeier   +3 more
wiley   +1 more source