Results 41 to 50 of about 396,749 (354)

Possible Role of N-Methyl-D-Aspartate Glutamate Receptors in The Induction of Acrosome Reaction in Human Sperm [PDF]

Cell Journal
Objective: Acrosome reaction is a receptor and Ca2+-dependent process. N-Methyl-D- aspartate (NMDA) glutamatereceptors are expressed in the human sperm and are involved in the Ca2+ influx.
Hamid Reza Momeni, Elham Farjad, Abolghasem Naiemi, Tahereh Etemadi, Mohammad Hussein Abnosi, Niloufar Darbandi   +5 more
doaj   +1 more source

Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. [PDF]

, 2013
Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored.
A McQuillin, A Scimemi, AA Boucher, AD Michel, AJ Law, AM Basso, AN Guerra, AV Gourine, B Sperlagh, B Sperlagh, B Sperlagh, Beáta Sperlágh, BP Guiard, C Csolle, C Delarasse, C Lavebratt, C Toro, C Verderio, Cecilia Csölle, CG Thomas, CM Anderson, DS Hasin, DT Balu, E Castren, E Fuchs, E Mundo, E Shimizu, E. Sylvester Vizi, Edit Papp, EJ Nestler, EK Green, F Frenois, F Karege, Flóra Gölöncsér, G Nagy, G Nowak, G Sanacora, G Sanacora, G Sanacora, Gabriella Zsilla, GE Hardingham, GE Wood, JE Malberg, JF Cryan, JF Cryan, JH Meador-Woodruff, JL Warner-Schmidt, JM Boyce-Rustay, JM Krueger, JO Groves, JS Barnholtz, K Hashimoto, K Hejjas, K Martinowich, K Viwatpinyo, K Wager-Smith, KR Tovar, L Backlund, L Bocchio-Chiavetto, L Papp, L Papp, L Patti, L Santarelli, L Stokes, L Zhang, LM Monteggia, M Baranyi, M Barbera-Cremades, M Diaz-Hernandez, M Grigoroiu-Serbanescu, M Koehl, M Masin, M Solle, ME Kozisek, ME Kozisek, ME Szapacs, ML Barbaccia, MT Miras-Portugal, MW Pfaffl, Mária Baranyi, N Barden, N Drigues, O Berton, OH Lowry, P Fossati, P Skolnick, P Soronen, P Vanhoutte, PA Lapchak, Peter Illes, R Dantzer, RC Hogg, RJ Griffiths, RJ Rodrigues, RS Duman, S Alloisio, S Duan, S Lucae, S Monleon, S Schnydrig, SN Williams, SP Banerjee, T Balazsa, T Deltheil, T Deltheil, T Zigova, Thierry Amédée, V Shukla, VF Labrousse, VM Brautigam, W Peng, Y Dwivedi, Y Shirayama, Z Hracskó, Ágnes Kittel   +114 more
core   +2 more sources

Signal Decoding for Glutamate Modulating Egg Laying Oppositely in Caenorhabditis elegans under Varied Environmental Conditions

iScience, 2020
Summary: Animals' ability to sense environmental cues and to integrate this information to control fecundity is vital for continuing the species lineage.
Xin Wen, Yuan-Hua Chen, Rong Li, Ming-Hai Ge, Sheng-Wu Yin, Jing-Jing Wu, Jia-Hao Huang, Hui Liu, Ping-Zhou Wang, Einav Gross, Zheng-Xing Wu   +10 more
doaj   +1 more source

Augmented Cystine–Glutamate Exchange by Pituitary Adenylate Cyclase-activating Polypeptide Signaling via the VPAC1 Receptor [PDF]

, 2014
In the central nervous system, cystine import in exchange for glutamate through system xc- is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of system
Arimura, Ashur-Fabian, Asztely, Baker, Baker, Baker, Bannai, Bannai, Barger, Berman, Brenneman, Brown, Chen, Choi, Costa, Diamond, Dickson, Dugan, Fahrenkrug, Figiel, Fogal, Ghatei, Grant, Grant, Grimaldi, Grimaldi, Groot, Hannibal, Hannibal, Hashimoto, Jackman, Johnson, Joo, Joo, Knackstedt, Kranich, Kupchik, Lewerenz, Liu, Liu, Liu, Liu, Lobner, Macdonald, Magistretti, Martin, Masmoudi-Kouki, Masmoudi-Kouki, Moran, Morio, Murphy, Park, Piani, Pow, Rush, Rush, Sagara, Said, Sato, Schwartz, Seaborn, Shih, Shintani, Sontheimer, Suh, Suzuki, Tatsuno, Tatsuno, Vaudry, Vaudry, Yaka, Ye, Yuhara, Zheng, Zhou   +74 more
core   +2 more sources

Glutamate receptors in the kidney [PDF]

Nephrology Dialysis Transplantation, 2015
l-Glutamate (l-Glu) plays an essential role in the central nervous system (CNS) as an excitatory neurotransmitter, and exerts its effects by acting on a large number of ionotropic and metabotropic receptors. These receptors are also expressed in several peripheral tissues, including the kidney.
openaire   +2 more sources

Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium

Cell Reports, 2015
GABAergic synaptic transmission regulates brain function by establishing the appropriate excitation-inhibition (E/I) balance in neural circuits.
Hiroko Bannai, Fumihiro Niwa, Mark W. Sherwood, Amulya Nidhi Shrivastava, Misa Arizono, Akitoshi Miyamoto, Kotomi Sugiura, Sabine Lévi, Antoine Triller, Katsuhiko Mikoshiba   +9 more
doaj   +1 more source

Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

eLife, 2020
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological
Damien Lemoine, Sarah Mondoloni, Jérome Tange, Bertrand Lambolez, Philippe Faure, Antoine Taly, Ludovic Tricoire, Alexandre Mourot   +7 more
doaj   +1 more source

Emotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction. [PDF]

, 2016
BACKGROUND: A difficult problem in treating opioid addicts is the maintenance of a drug-free state because of the negative emotional symptoms associated with withdrawal, which may trigger relapse.
Bailey, A, Chen, Y, Georgiou, P, Gonzalez, LR, Hourani, S, Kieffer, BL, Kitchen, I, Winsky-Sommerer, R, Zanos, P   +8 more
core   +1 more source

Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds. [PDF]

PLoS ONE, 2012
Recent studies suggest that l-glutamate may be an efferent transmitter released from axons innervating taste buds. In this report, we determined the types of ionotropic synaptic glutamate receptors present on taste cells and that underlie this postulated
Yijen A Huang, Jeff Grant, Stephen Roper
doaj   +1 more source

The Role of Glutamate Receptors in Epilepsy

Biomedicines, 2023
Glutamate is an essential excitatory neurotransmitter in the central nervous system, playing an indispensable role in neuronal development and memory formation. The dysregulation of glutamate receptors and the glutamatergic system is involved in numerous
Tsang-Shan Chen, Tzu-Hsin Huang, Ming-Chi Lai, Chin-Wei Huang   +3 more
doaj   +1 more source