Results 191 to 200 of about 311,002 (284)

Glutamate receptor (NMDA receptor) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

The gating properties of Drosophila NMJ glutamate receptors and their dependence on Neto. [PDF]

J Physiol
Han TH, Vicidomini R, Ramos CI, Mayer ML, Serpe M.   +4 more
europepmc   +1 more source

Dietary Glutamine Supplementation Alleviated Rumen Epithelium Oxidative Damage and Apoptosis Induced by Feed Restriction via Maintaining Mitochondrial Homeostasis in Female Yaks

Animal Research and One Health, EarlyView.
Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue, Shanpeng Ke, Liyuan Shi, Rui Hu, Zhisheng Wang, Quanhui Peng, Huawei Zou, Jianxin Xiao, Yahui Jiang, Fali Wu, Yiping Tang   +10 more
wiley   +1 more source

Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Di Menna L, Alborghetti M, De Bartolo MI, Borro M, Gentile G, Zinni M, Bologna M, Cutrona C, D'Errico G, Imbriglio T, Bucci D, Merlo S, Ginerete RP, Orlando R, Carrillo F, Fortunato G, Cannella M, Sortino MA, Pansiot J, Baud O, Nicoletti F, Bruno V, Simmaco M, Pontieri FE, Bianchini E, Rinaldi D, de Curtis A, De Gaetano G, Iacoviello L, Esposito T, Berardelli A, Battaglia G.   +31 more
europepmc   +1 more source

Tissue‐specific and spatially dependent metabolic signatures perturbed by injury in male and female mice

Arthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis—the leading cause of disability worldwide—disproportionately affects females, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

Synaptic Plasticity Linked to Ionotropic Glutamate Receptors After Nicotine Exposure. [PDF]

Curr Neuropharmacol
Kazmi A, Choe ES.
europepmc   +1 more source

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study. [PDF]

Alzheimers Res Ther
Salardini E, O'Dell RS, Tchorz E, Nabulsi NB, Huang Y, Carson RE, van Dyck CH, Mecca AP.   +7 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source